HYPERURICEMIA IN PRIMARY AND RENAL HYPERTENSION
HYPERURICEMIA IN PRIMARY AND RENAL HYPERTENSION
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DOI：
10.1056/nejm196609012750902
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发表时间：
1966-01-01
影响因子：
158.5
通讯作者：
LARAGH, JH
中科院分区：
文献类型：
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作者：
CANNON, PJ;STASON, WB;LARAGH, JH
123目前对纽约市长老会医院高血压-肾炎诊所人群的调查证实，在经过治疗和未经治疗的原发性高血压或肾性高血压患者中，这一观察结果得到了证实。来自一系列相关研究的数据表明，这两种类型的高血压的高尿酸血症都是由于肾脏尿酸盐排泄减少所致。高血压病中乳酸代谢的改变可能是尿酸肾脏转运改变的部分原因。4研究结果也增加了……升高的可能性。
AN increased incidence of hyperuricemia in patients with primary hypertension has been cited in several reports.123The present investigation of the population of the Hypertension-Nephritis Clinic of the Presbyterian Hospital in New York City confirms this observation among patients with either primary or renal hypertension, treated and untreated. The data from a related series of studies suggest that the hyperuricemia in both types of hypertension results from diminished renal excretion of urate. Altered lactic acid metabolism in hypertensive disease may account in part for the altered renal transport of uric acid.4The results also raise the possibility that elevations of . . .