Association between erectile dysfunction and coronary artery disease.: Role of coronary clinical presentation and extent of coronary vessels involvement:: the COBRA trial
Association between erectile dysfunction and coronary artery disease.: Role of coronary clinical presentation and extent of coronary vessels involvement:: the COBRA trial
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DOI：
10.1093/eurheartj/ehl142
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发表时间：
2006-11-01
影响因子：
39.3
通讯作者：
Fiorentini, Cesare
中科院分区：
文献类型：
--
作者：
Montorsi, Piero;Ravagnani, Paolo M.;Fiorentini, Cesare
目的 根据临床表现、急性冠脉综合征 (ACS) 与慢性冠脉综合征 (CCS) 以及血管受累程度（单支血管病变与多支血管病变），调查 CAD 患者勃起功能障碍 (ED) 的患病率。方法和结果 将 285 名 CAD 患者分为三个年龄匹配组：第 1 组（G1，n=95）、ACS 和单支血管病变（1-VD）；第 2 组（G2，n=95），ACS 和 2,3-VD；第 3 组（G3，n=95），慢性 CS。对照组（C，n=95）由疑似 CAD 患者组成，经血管造影发现冠状动脉完全正常。 Gensini 评分用于评估 CAD 的程度。根据国际勃起功能指数 (IIEF)，ED 为 < 26 的任意值。 G1 的 ED 患病率低于 G3（22% vs. 65%，P
Aims To investigate the prevalence of erectile dysfunction (ED) in patients with CAD according to clinical presentation, acute coronary syndrome (ACS) vs. chronic coronary syndrome (CCS), and extent of vessel involvement (single vs. multi-vessel disease).Methods and results 285 patients with CAD divided into three age-matched groups: group 1 (G1, n=95), ACS and one-vessel disease (1-VD); group 2 (G2, n=95), ACS and 2,3-VD; group 3 (G3, n=95), chronic CS. Control group (C, n=95) was composed of patients with suspected CAD who were found to have entirely normal coronary arteries by angiography. Gensini's score used to assess extent of CAD. ED as any value < 26 according to the International Index of Erectile Function (IIEF). ED prevalence was lower in G1 vs. G3 (22 vs. 65%, P