Priorities for cancer research in low- and middle-income countries: a global perspective.

Priorities for cancer research in low- and middle-income countries: a global perspective.
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DOI:
10.1038/s41591-022-01738-x
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发表时间:
2022-04
期刊:
影响因子:
82.9
通讯作者:
Weiderpass, Elisabete
Weiderpass, Elisabete
中科院分区:
医学1区
文献类型:
--
作者:
Pramesh, C. S.;Badwe, Rajendra A.;Bhoo-Pathy, Nirmala;Booth, Christopher M.;Chinnaswamy, Girish;Dare, Anna J.;de Andrade, Victor Piana;Hunter, David J.;Gopal, Satish;Gospodarowicz, Mary;Gunasekera, Sanjeeva;Ilbawi, Andre;Kapambwe, Sharon;Kingham, Peter;Kutluk, Tezer;Lamichhane, Nirmal;Mutebi, Miriam;Orem, Jackson;Parham, Groesbeck;Ranganathan, Priya;Sengar, Manju;Sullivan, Richard;Swaminathan, Soumya;Tannock, Ian F.;Tomar, Vivek;Vanderpuye, Verna;Varghese, Cherian;Weiderpass, Elisabete

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癌症研究目前严重偏向于高收入国家(HIC),很少有研究在低收入和中等收入国家(LMIC)的问题上进行。需要重新平衡癌症知识生成和应用方面的这种区域性不一致。需要解决中低收入国家研究事业中的一些差距,以促进区域相关研究,并需要彻底反思,以解决这些地区癌症护理中的紧迫问题。我们根据当前和预计的需求确定了中低收入国家癌症研究的五个首要任务:减轻晚期疾病患者的负担;改善癌症治疗的可及性和可负担性以及结果;基于价值的护理和卫生经济学;质量改进和实施研究;利用技术改善癌症控制。中低收入国家有很好的机会来解决癌症研究中可能影响全球癌症控制的重要问题。成功将需要政府、决策者、资助机构、卫生保健组织和领导人、研究人员和公众的合作和承诺。
Cancer research currently is heavily skewed toward high-income countries (HICs), with little research conducted in, and relevant to, the problems of low- and middle-income countries (LMICs). This regional discordance in cancer knowledge generation and application needs to be rebalanced. Several gaps in the research enterprise of LMICs need to be addressed to promote regionally relevant research, and radical rethinking is needed to address the burning issues in cancer care in these regions. We identified five top priorities in cancer research in LMICs based on current and projected needs: reducing the burden of patients with advanced disease; improving access and affordability, and outcomes of cancer treatment; value-based care and health economics; quality improvement and implementation research; and leveraging technology to improve cancer control. LMICs have an excellent opportunity to address important questions in cancer research that could impact cancer control globally. Success will require collaboration and commitment from governments, policy makers, funding agencies, health care organizations and leaders, researchers and the public.
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