Gain modulation of the middle latency cutaneous reflex in patients with chronic joint instability after ankle sprain
Gain modulation of the middle latency cutaneous reflex in patients with chronic joint instability after ankle sprain
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DOI：
10.1016/j.clinph.2013.01.029
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发表时间：
2013-07-01
影响因子：
4.7
通讯作者：
Komiyama, Tomoyoshi
中科院分区：
文献类型：
--
作者：
Futatsubashi, Genki;Sasada, Shusaku;Komiyama, Tomoyoshi
目的：探讨慢性踝关节不稳定患者皮肤传入神经反射通路的神经改变。方法：通过对坐位的慢性踝关节不稳定受试者（n = 17）和对照受试者（n = 17）的腓肠神经施加无害性电刺激来诱发皮肤反射。记录每个脚踝和大腿肌肉的肌电图 (EMG) 信号。分析中潜伏期反应（MLR；潜伏期：70-120 ms）成分。 结果：在腓骨长肌（PL）和股外侧肌（VL）中，抑制性 MLR 强度与背景 EMG 活动之间的线性回归分析表明，与未受伤侧和对照受试者相比，受伤侧抑制性 MLR 的增益增加。两组的汇总数据也证实了这一点。 MLR 改变的程度与 PL 慢性踝关节不稳显着相关。结论：慢性踝关节不稳定受试者中 PL 和 VL 中潜伏期皮肤反射的兴奋性受到调节。意义：皮肤反射可能是研究慢性踝关节不稳定受试者控制下肢神经系统病理状态的潜在工具。 (c) 2013 年国际临床神经生理学联合会。由爱思唯尔爱尔兰有限公司出版。保留所有权利。
Objective: To investigate the neural alteration of reflex pathways arising from cutaneous afferents in patients with chronic ankle instability.Methods: Cutaneous reflexes were elicited by applying non-noxious electrical stimulation to the sural nerve of subjects with chronic ankle instability (n = 17) and control subjects (n = 17) while sitting. Electromyographic (EMG) signals were recorded from each ankle and thigh muscle. The middle latency response (MLR; latency: 70-120 ms) component was analyzed.Results: In the peroneus longus (PL) and vastus lateralis (VL) muscles, linear regression analyses between the magnitude of the inhibitory MLR and background EMG activity showed that, compared to the uninjured side and the control subjects, the gain of the suppressive MLR was increased in the injured side. This was also confirmed by the pooled data for both groups. The degree of MLR alteration was significantly correlated to that of chronic ankle instability in the PL.Conclusions: The excitability of middle latency cutaneous reflexes in the PL and VL is modulated in subjects with chronic ankle instability.Significance: Cutaneous reflexes may be potential tools to investigate the pathological state of the neural system that controls the lower limbs in subjects with chronic ankle instability. (c) 2013 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.