Results of extended surgery for cancer of the rectum and sigmoid

Results of extended surgery for cancer of the rectum and sigmoid
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直肠癌和乙状结肠癌扩大手术的结果

DOI:
10.1002/bjs.1800690603
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发表时间:
1982
影响因子:
9.6
通讯作者:
L. Gennari
L. Gennari
中科院分区:
医学1区
文献类型:
--
作者:
G. Bonfanti;F. Bozzetti;R. Doci;F. Baticci;R. Marolda;P. Bignami;L. Gennari

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本文回顾了1965 ~ 1977年间61例直肠癌和乙状结肠癌扩大手术的临床资料。41例行腹会阴联合切除术,18例行前切除术,2例行Hartmann切除术。术后死亡率为8.2%,非致死性发病率为30.3%,但4例患者出现多种并发症。对同时切除的组织中有或没有肿瘤浸润的显微镜证据的患者分别评估5年生存率;第一组为32%,第二组为75%; 66%的显微镜浸润患者和24%的无显微镜浸润患者发生局部或远处复发。这些结果与直肠和乙状结肠的Dukes' C癌的普通切除术后报告的结果相比是有利的,并且似乎证明当直肠和乙状结肠癌侵犯邻近结构时使用扩大手术是合理的。
The clinical records of 61 patients who underwent extended surgery, including resection of parietes or other viscera, from 1965 to 1977 for cancer of the rectum and sigmoid were reviewed. Abdominoperineal resection was performed in 41 patients, anterior resection in 18 and Hartmann's resection in 2. The postoperative mortality rate was 8·2 per cent, the non‐lethal morbidity rate 30·3 per cent, but 4 patients presented multiple complications. The 5‐year survival rate was evaluated separately for patients with and without microscopic evidence of neoplastic involvement of the simultaneously excised structures; in the first group it was 32 per cent, in the second 75 per cent. Local or distant recurrence occurred in 66 per cent of patients with microscopic infiltration and in 24 per cent of patients without microscopic infiltration. These results compare favourably with those reported after ordinary resections of Dukes' C cancers of the rectum and sigmoid, and seem to justify the use of extended surgery when cancer of the rectum and sigmoid has invaded contiguous structures.