Comparison of Right Ventricle Morphological and Mechanical Characteristics for Healthy and Patients with Tetralogy of Fallot: An In Vivo MRI-Based Modeling Study.
Comparison of Right Ventricle Morphological and Mechanical Characteristics for Healthy and Patients with Tetralogy of Fallot: An In Vivo MRI-Based Modeling Study.
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DOI：
10.3970/mcb.2017.014.137
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Geva T
中科院分区：
文献类型：
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作者：
Tang D;Zuo H;Yang C;Wu Z;Huang X;Rathod RH;Tang A;Billiar KL;Geva T
法洛四联症（TOF）修复患者占迟发性右心室衰竭病例的大多数。将 TOF 患者与健康人进行比较可能会提供应对这一挑战的信息。心脏磁共振（CMR）数据来自 16 名 TOF 患者（患者组，PG）和 6 名健康志愿者（健康组，HG）。在射血开始时，较好的患者组（n=5，BPG）压力非常接近 HG 压力（54.7±38.4 kPa vs. 51.2±55.7 kPa，p=0.6889），而较差的患者组（n=11，WPG）压力比 HG 压力高 84%（p=0.0418）。经进一步验证，压力可作为区分 BPG 患者与 WPG 患者的指标。
Patients with repaired tetralogy of Fallot (TOF) account for the majority of cases with late onset right ventricle failure. Comparing TOF patients with healthy people may provide information to address this challenge. Cardiac magnetic resonance (CMR) data were obtained from 16 TOF patients (patient group, PG) and 6 healthy volunteers (healthy group, HG). At begin-of-ejection, better patient group (n=5, BPG) stress was very close to HG stress (54.7±38.4 kPa vs. 51.2±55.7 kPa, p=0.6889) while worse patient group (n=11, WPG) stress was 84% higher than HG stress (p=0.0418). Stress may be used as an indicator to differentiate BPG patients from WPG patients, with further validations.