Use of human papillomavirus vaccines among young adult women in the United States: An analysis of the 2008 National Health Interview Survey
Use of human papillomavirus vaccines among young adult women in the United States: An analysis of the 2008 National Health Interview Survey
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DOI：
10.1002/cncr.26244
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发表时间：
2011-12-15
期刊：
影响因子：
6.2
通讯作者：
Breen, Nancy
中科院分区：
文献类型：
--
作者：
Price, Rebecca Anhang;Tiro, Jasmin A.;Breen, Nancy
背景：疾病控制和预防中心建议对13至26岁以前未接种过疫苗的女孩和妇女补充接种人乳头状瘤病毒(HPV)疫苗。为了回应关于年轻成年妇女补种疫苗的辩论，这项研究调查了最有可能从补种中受益的18至26岁妇女是否知道HPV疫苗，并在2008年底之前启动了疫苗系列。方法：我们使用2008年全国健康访谈调查的数据来评估18-26岁女性(n=1583)对HPV疫苗的知晓和使用情况，以及没有接种疫苗的原因。使用多变量Logistic回归对与疫苗接种相关的社会人口学、卫生保健途径和健康史因素进行评估。结果：总体而言，截至2008年底，11.7%的18-26岁妇女报告接种了至少一剂HPV疫苗。在多因素分析中，较年轻的年龄、既往HPV感染史、未婚状态、健康保险、过去一年接种流感疫苗以及接受1种或1种以上推荐的终身疫苗接种与HPV疫苗接种显著相关。五分之二(39.6%)的未接种妇女对接种HPV疫苗感兴趣(1327人)。对疫苗缺乏兴趣的主要原因是相信它是不需要的，对它了解不够，对安全性的担忧，以及不活跃的性行为。结论：青壮年女性HPV疫苗接种率较低，未参保者低于参保者。公共融资和护理提供计划有可能扩大未参保妇女的疫苗覆盖面，这些妇女患宫颈癌的风险增加。癌症杂志2011；117：5560-8。(C)2011年美国癌症协会。
BACKGROUND: The Centers for Disease Control and Prevention recommends catch-up administration of human papillomavirus (HPV) vaccines to girls and women ages 13 to 26 who have not been vaccinated previously. In response to debate regarding catch-up vaccination of young adult women, this study examined whether 18- to 26-year-old women most likely to benefit from catch-up vaccination were aware of the HPV vaccine, and initiated the vaccine series by the end of 2008. METHODS: We used data from the 2008 National Health Interview Survey to assess HPV vaccine awareness and use, and reasons for not vaccinating, among women aged 18-26 years (n = 1583). Sociodemographic, health care access, and health history factors associated with vaccine initiation were assessed using multivariate logistic regression. RESULTS: Overall, 11.7% of women aged 18-26 years reported receiving at least 1 dose of the HPV vaccine by the end of 2008. In multivariate analyses, younger age, history of previous HPV infection, unmarried status, health insurance, flu shot in the past year, and receipt of 1 or more recommended lifetime vaccines were significantly associated with HPV vaccine initiation. Two-fifths (39.6%) of unvaccinated women were interested in receiving the HPV vaccine (n 1327). Primary reasons for lack of interest in the vaccine were belief that it was not needed, not knowing enough about it, concerns about safety, and not being sexually active. CONCLUSION: HPV vaccine coverage among young adult women was low, and lower among the uninsured than the insured. Public financing and care provision programs have the potential to expand vaccine coverage among uninsured women, who are at increased risk of cervical cancer. Cancer 2011; 117: 5560-8. (C) 2011 American Cancer Society.