Pulmonary vein ostium shape and orientation as possible predictors of occlusion in patients with drug-refractory paroxysmal atrial fibrillation undergoing cryoballoon ablation
Pulmonary vein ostium shape and orientation as possible predictors of occlusion in patients with drug-refractory paroxysmal atrial fibrillation undergoing cryoballoon ablation
复制标题
DOI：
10.1093/europace/euq388
复制
发表时间：
2011-02-01
期刊：
影响因子：
6.1
通讯作者：
Brugada, Pedro
中科院分区：
文献类型：
--
作者：
Sorgente, Antonio;Chierchia, Gian Battista;Brugada, Pedro
目的没有具体的数据是可用的肺静脉（PV）的解剖结构和形状对冷冻球囊消融（CA）导管的疗效，提供冷冻能量，因此，在获得PV isolation.Methods和结果之间的一个较大的系列（68）药物难治性阵发性心房颤动谁在我们的部门接受CA的患者，52例被纳入我们的研究。所有患者术前均行多层心脏计算机断层扫描（MSCT）。我们回顾性评价了他们的MSCT扫描，重点关注额状面的肺静脉椭圆度和方向。左肺静脉的椭圆度指数和闭塞程度之间存在一定的负相关性（LSPV的r = -0.486和P = 0.003，LIPV的r = -0.360和P = 0.033），而右肺静脉椭圆度指数与闭塞程度无相关性（RSPV的r = -0.283和P = 0.083; RIPV的r = 0.235和P = 0.093）。然而，肺静脉口的方向和每条静脉的闭塞程度之间存在很强的负相关性（LSPV的r = -0.804和P < 0.001，LIPV的r = -0.415和P = 0.013，RSPV的r = -0.798和P = 0.001，结论MSCT测量肺静脉口的形态和方向对预测CA术中肺静脉阻塞程度有一定的价值。
Aims No specific data are available on the influence of pulmonary vein (PV) anatomy and shape on cryoballoon ablation (CA) catheter efficacy in delivering cryothermal energy and, consequently, in obtaining PV isolation.Methods and results Among a larger series of patients (68) with drug-refractory paroxysmal atrial fibrillation who underwent CA in our department, 52 patients were included in our study. All of them had a multislice cardiac computed tomography (MSCT) before the procedure. We retrospectively evaluated their MSCT scans focusing our attention on PV ovality and orientation in the frontal plane. A fair inverse association was documented between the ovality index of the left PVs and the degree of occlusion (r = -0.486 and P = 0.003 for the LSPV and r = -0.360 and P = 0.033 for the LIPV), whereas no association was found between the ovality index of the right PVs and the degree of occlusion (r = -0.283 and P = 0.083 for the RSPV and r = 0.235 and P = 0.093 for RIPV). Nevertheless, a strong inverse association was found between the orientation of the PV ostia and the degree of occlusion in each vein (r = -0.804 and P < 0.001 for the LSPV, r = -0.415 and P = 0.013 for LIPV, r = -0.798 and P = 0.001 for the RSPV, and r = -0.867 and P < 0.001 for RIPV).Conclusion Pulmonary vein ostium shape and orientation evaluated by MSCT proved to be useful in predicting the degree of occlusion obtained during CA.