An analysis of anemia and pregnancy-related maternal mortality
An analysis of anemia and pregnancy-related maternal mortality
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DOI：
10.1093/jn/131.2.604s
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发表时间：
2001-02-01
影响因子：
4.2
通讯作者：
Pelletier, D
中科院分区：
文献类型：
--
作者：
Brabin, BJ;Hakimi, M;Pelletier, D
由于无法进行随机试验分析，因此通过横断面研究、纵向研究和病例对照研究来分析贫血作为孕产妇死亡危险因素的关系。采用以下六种死亡风险估算方法： I) 国家统计数据得出的孕产妇死亡率与孕产妇贫血患病率的相关性； 2) 因贫血导致的孕产妇死亡比例； 3) 贫血女性死亡比例； 4) 因贫血导致孕产妇死亡的人群归因风险； 5) 青春期是贫血相关死亡的危险因素； 6) 与孕产妇死亡相关的贫血原因。非洲、亚洲和拉丁美洲全因贫血死亡率（直接和间接）的平均估计值分别为 6.37%、7.26% 和 3.0%。主要针对医院研究的病死率从 50% 不等。中度贫血（血红蛋白 40-80 g/L）相关的死亡相对风险为 1.35 [95% 置信区间 (GI)：0.92-2.00]，重度贫血（血红蛋白 40-80 g/L）相关的死亡相对风险为 1.35
The relationship of anemia as a risk factor for maternal mortality was analyzed by using cross-sectional, longitudinal and case-control studies because randomized trials were not available for analysis. The following six methods of estimation of mortality risk were adopted: I) the correlation of maternal mortality rates with maternal anemia prevalence derived from national statistics; 2) the proportion of maternal deaths attributable to anemia; 3) the proportion of anemic women who die; 4) population-attributable risk of maternal mortality due to anemia; 5) adolescence as a risk factor for anemia-related mortality; and 6) causes of anemia associated with maternal mortality. The average estimates for all-cause anemia attributable mortality (both direct and indirect) were 6.37, 7.26 and 3.0% for Africa, Asia and Latin America, respectively. Case fatality rates, mainly for hospital studies, varied from 50%. The relative risk of mortality associated with moderate anemia (hemoglobin 40-80 g/L) was 1.35 [95% confidence interval (GI): 0.92-2.00] and for severe anemia (