INCIDENCE OF CONGENITAL-ANOMALIES AMONG WHITE AND BLACK LIVE BIRTHS WITH LONG-TERM FOLLOW-UP
INCIDENCE OF CONGENITAL-ANOMALIES AMONG WHITE AND BLACK LIVE BIRTHS WITH LONG-TERM FOLLOW-UP
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DOI：
10.2105/ajph.71.12.1333
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发表时间：
1981-01-01
影响因子：
12.7
通讯作者：
OECHSLI, FW
中科院分区：
文献类型：
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作者：
CHRISTIANSON, RE;VANDENBERG, BJ;OECHSLI, FW
在一项大型前瞻性研究中，介绍了活产儿童出生时和累积至5岁时先天性畸形的发生率。先天性畸形并非都是在出生时就能诊断出来的，发病率也在增加。在6日龄至5岁之间，黑人为3 1/2倍，白人为5倍。黑人儿童出生时先天性畸形的发生率高于白色儿童，但两组之间累积到5岁的发生率没有显著差异。5年时，重度和中度（但并非微不足道）先天性异常的发生率为15%;重度先天性异常为4%。在出生时体重2500克或更轻的儿童中，观察到在5岁之前诊断出的严重先天性畸形的发生率比那些更重的儿童高得多。
The incidence of congenital anomalies at birth and accumulated to age 5 yr is presented for live-born children in a large prospective study. Congenital anomalies are not all diagnosable at birth; the incidence rate increases .apprx. 3 1/2-fold for Blacks and 5-fold for Whites between 6 days of age and 5 yr of age. The incidence of congenital anomalies at birth was higher among Black children than White children, but there were no notable differences between the groups in incidence accumulated to age 5 yr. At 5 yr, the incidence rate of severe and moderate (but not trivial) congenital anomalies amounted to 15%; for severe congenital anomalies, 4%. Severe congenital anomalies diagnosed through age 5 yr were observed to have a much higher incidence among children who weighed 2500 gm or less at birth than among those who were heavier.