High prevalence of metallo-β-lactamase and 16S rRNA methylase coproduction among imipenem-resistant Pseudomonas aeruginosa isolates in Brazil
High prevalence of metallo-β-lactamase and 16S rRNA methylase coproduction among imipenem-resistant Pseudomonas aeruginosa isolates in Brazil
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DOI：
10.1128/aac.00443-07
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发表时间：
2007-09-01
影响因子：
4.9
通讯作者：
Paterson, David L.
中科院分区：
文献类型：
--
作者：
Doi, Yohei;Ghilardi, Angela C. R.;Paterson, David L.
从巴西巴罗保罗州的医院收集了51株耐亚胺培南铜绿假单胞菌临床分离株，研究了金属β-内酰胺酶和16 S rRNA甲基化酶的产生率。其中，57%和75%分别产生SPM-1和RmtD。值得注意的是，51%的人同时产生这两种酶，这表明它们的联合生产在这个地理区域已经很常见。
Rates of metallo-beta-lactamase and 16S rRNA methylase production were investigated in 51 imipenem-resistant Pseudomonas aeruginosa clinical isolates collected from hospitals in S (a) over baro Paulo, Brazil. Of them, 57% and 75% produced SPM-1 and RmtD, respectively. Of note, 51% produced both enzymes, suggesting that their coproduction is already common in this geographic area.