Prevalence of dementia in the united states: The aging, demographics, and memory study
Prevalence of dementia in the united states: The aging, demographics, and memory study
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DOI：
10.1159/000109998
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发表时间：
2007-01-01
影响因子：
5.7
通讯作者：
Wallace, R. B.
中科院分区：
文献类型：
--
作者：
Plassman, B. L.;Langa, K. M.;Wallace, R. B.
目的：使用全国代表性样本估计美国阿尔茨海默病（AD）和其他痴呆症的患病率。研究方法：老龄化，人口统计学和记忆研究样本由856名来自全国代表性健康和退休研究（HRS）的71岁及以上的人组成，他们使用全面的家庭评估进行痴呆症评估。专家共识小组使用这些信息来分配正常认知，认知障碍但不是痴呆或痴呆（和痴呆亚型）的诊断。使用来自HRS的抽样权重，我们估计了痴呆，AD和血管性痴呆的年龄和性别的全国患病率。结果：2002年，美国71岁及以上人群中痴呆的患病率为13.9%，约为340万人。AD的相应值为9.7%和240万人。痴呆症患病率随着年龄的增长而增加，从71 - 79岁的5.0%增加到90岁及以上的37.4%。结论：从这第一个全国代表性的基于人群的痴呆症研究中估计痴呆症患病率，包括来自全国所有地区的受试者，可以为有效规划大量和越来越多的痴呆症风险个体的迫在眉睫的医疗保健需求提供重要信息。版权所有（c）2007 S. Karger AG，巴塞尔。
Aim: To estimate the prevalence of Alzheimer's disease (AD) and other dementias in the USA using a nationally representative sample. Methods: The Aging, Demographics, and Memory Study sample was composed of 856 individuals aged 71 years and older from the nationally representative Health and Retirement Study (HRS) who were evaluated for dementia using a comprehensive in-home assessment. An expert consensus panel used this information to assign a diagnosis of normal cognition, cognitive impairment but not demented, or dementia (and dementia subtype). Using sampling weights derived from the HRS, we estimated the national prevalence of dementia, AD and vascular dementia by age and gender. Results: The prevalence of dementia among individuals aged 71 and older was 13.9%, comprising about 3.4 million individuals in the USA in 2002. The corresponding values for AD were 9.7% and 2.4 million individuals. Dementia prevalence increased with age, from 5.0% of those aged 71 - 79 years to 37.4% of those aged 90 and older. Conclusions: Dementia prevalence estimates from this first nationally representative population-based study of dementia in the USA to include subjects from all regions of the country can provide essential information for effective planning for the impending healthcare needs of the large and increasing number of individuals at risk for dementia as our population ages. Copyright (c) 2007 S. Karger AG, Basel.