COMPARISON OF THE PRECISION OF 2 STANDARDIZED COORDINATE SYSTEMS FOR THE QUANTITATION OF BRAIN ANATOMY - PRELIMINARY-RESULTS

COMPARISON OF THE PRECISION OF 2 STANDARDIZED COORDINATE SYSTEMS FOR THE QUANTITATION OF BRAIN ANATOMY - PRELIMINARY-RESULTS
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DOI:
10.1007/bf00593507
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发表时间:
1994-10-01
期刊:
影响因子:
2.8
通讯作者:
ALBERT, M
ALBERT, M
中科院分区:
医学3区
文献类型:
--
作者:
SANDOR, T;TIEMAN, J;ALBERT, M

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我们评估了两个标准化的坐标系统的可重复定义的脑图像的受试者间分析。两个坐标系中的基线是鼻道(mCM)线和前后连合(AC-PC)线的修改。使用了4名受试者在1.5T下的轴向自旋回波MR图像。根据两名操作员的重复分析计算操作员误差。mCM线由眼的透镜和内耳道确定,AC-PC线由AC和PC与纵裂的交点确定。mCM标记物的重现性(SD = 0.59 mm)与AC-PC系的重现性(SD = 0.68 mm)无显著差异。然而,AC-PC线的基线角度(Δ α)的测量误差是mCM线的7倍多。影响坐标系头尾旋转的另一个误差(归因于解剖标记之间的距离)对于mCM坐标系为2.1和3.6度(3 mm和5 mm切片厚度),对于AC-PC系统为8.2和11.0度(3 mm和5 mm切片厚度)。因此,基于AC-PC线的坐标系统的再现性低于基于mCM线的系统。如果结合轴位和矢状位图像来定义AC-PC线,则可以改善这一点。
We assessed reproducible definition of two standardized co-ordinate systems for intersubject analysis of brain images. The baselines in the two co-ordinate systems were a modification of the canthomeatal (mCM) line and the anterior-posterior commissural (AC-PC) line. Axial spin-echo MR images of four subjects at 1.5T were used. Operator error was computed from the replicate analyses of two operators. The mCM line was determined by the lens of the eye and the inter nai auditory canal, and the AC-PC line was determined by the intersection of the AC and PC with the interhemispheric fissure. Reproducibility of the mCM markers (SD = 0.59 mm) did not differ significantly from that of the AC-PC line (SD = 0.68 mm). The measurement error of the angle of the baseline (delta alpha), however, was more than 7 times as large for the AC-PC line as for the mCM line. An additional error affecting the rostrocaudal rotation of the co-ordinate systems, attributable to the distance between the anatomic markers, was 2.1 and 3.6 degrees (3 mm and 5 mm slice thickness) for the mCM co-ordinate system and 8.2 and 11.0 degrees (3 mm and 5 mm slice thickness) for the AC-PC system. The AC-PC line based co-ordinate system is therefore, less reproducible than the mCM line based system. This could be improved if a combination of axial and sagittal images were used for the definition of the AC-PC line.