Evaluation of Elective Irradiation of the Neck for Squamous-Cell Carcinoma of the Nasopharynx, Tonsillar Fossa, and Base of Tongue
Evaluation of Elective Irradiation of the Neck for Squamous-Cell Carcinoma of the Nasopharynx, Tonsillar Fossa, and Base of Tongue
复制标题
颈部选择性放射治疗鼻咽、扁桃体窝和舌根鳞状细胞癌的评估
作者：
R. Million;G. Fletcher;R. Jesse
鼻咽癌、扁桃体窝癌和舌根癌通过手术切除或放射消毒显微病变来预防颈部淋巴结转移的价值一直备受争议。根治性颈淋巴清扫术或颈部放射治疗没有临床可触及的结节，通常被称为“预防性”处理。然而，“选择性”治疗在概念上更正确，本文的目的是分析颈部选择性放射治疗获得的经验，以确定这是否是一种对高转移侵袭性癌症有用且安全的技术。文献综述关于唇癌和口腔癌颈部“预防性照射”的文献报道不多(2、4、8、10、11、14)。几位作者的共识是，无论是颈部淋巴结的后续发展还是五年的生存期，预防性照射组都没有差别。
The value of preventing metastases to the lymph nodes of the neck in carcinoma of the nasopharynx, tonsillar fossa, and base of tongue by either surgical removal or sterilization of microscopic disease with radiation has been much debated. Radical neck dissection or irradiation of the neck without clinically palpable nodes has often been referred to as “prophylactic” management. However, “elective” management is conceptually more correct, and the purpose of this paper is to analyze experience acquired with elective irradiation of the neck to determine if this is a useful and safe technic in cancers with high metastatic aggressiveness. Review of the Literature A few reports were found in the literature on “prophylactic irradiation” of the neck for carcinomas arising from the lip and oral cavity (2, 4, 8, 10, 11, 14). The consensus among the several authors was that there is no difference in either the subsequent development of neck nodes or the five-year survivals when the groups with “prophylactic irradia...