Evaluation of P-POSSUM and CR-POSSUM Scores in Patients with Colorectal Cancer Undergoing Resection
Evaluation of P-POSSUM and CR-POSSUM Scores in Patients with Colorectal Cancer Undergoing Resection
复制标题
结直肠癌切除患者的 P-POSSUM 和 CR-POSSUM 评分评估
作者：
M. Tez;Ö. Yoldaş;E. Gocmen;Bahadır Külah;M. Koç
Introduction本研究的目的是评估预测准确性P-POSSUM和CR-POSSUM模型对患者接受结直肠surgery.MethodsP-POSSUM和CR-POSSUM预测方程的死亡率进行了回顾性的321例患者接受结直肠切除术的癌症。P-POSSUM和CR-POSSUM评分通过评估其校准和区分度进行验证。使用Hosmer-Lemeshow拟合优度检验和相应的校准曲线评估校准。使用受试者工作特征（ROC）曲线analysis.ResultsOverall，观察到22例死亡的判别能力的两个模型进行评估。CR-POSSUM预测死亡25例（χ2 = 12.20，P = 0.13），P-POSSUM预测死亡29例（χ2 =18.85，P = 0.002）。ROC曲线分析显示CR-POSSUM对死亡率有合理的判别力。结论CR-POSSUM对结直肠切除术后患者的死亡风险有较好的估计价值。
IntroductionThe aim of this study was to evaluate the predictive accuracy of P-POSSUM and CR-POSSUM models on patients undergoing colorectal resection.MethodsP-POSSUM and CR-POSSUM predictor equations for mortality were applied retrospectively to 321 patients who had undergone colorectal resection for cancer. P-POSSUM and CR-POSSUM scores were validated by assessing their calibration and discrimination. Calibration was assessed using the Hosmer-Lemeshow goodness-of-fit test and the corresponding calibration curves. Evaluation of the discriminative capability of both models was performed using receiver-operating characteristic (ROC) curve analysis.ResultsOverall, 22 deaths were observed. CR-POSSUM predicted 25 deaths (χ2 = 12.20, P = 0.13), and P-POSSUM predicted 29 deaths (χ2 =18.85, P = 0.002). ROC curves analysis revealed that CR-POSSUM has reasonable discriminatory power for mortality.ConclusionsThese data suggest that CR-POSSUM may provide a better estimate of the risk of mortality for patients who undergoing colorectal resection.