CNS demyelination associated with copper deficiency and hyperzincemia
CNS demyelination associated with copper deficiency and hyperzincemia
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DOI：
10.1001/archneur.59.9.1453
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发表时间：
2002-11-12
期刊：
影响因子：
9.9
通讯作者：
Bottomley, SS
中科院分区：
文献类型：
--
作者：
Prodan, CI;Holland, NR;Bottomley, SS
CNS demyelination is not a previously reported feature of acquired copper deficiency. The authors report two patients with idiopathic hypocupremia and hyperzincemia, hematologic changes of copper deficiency, and extensive CNS demyelination. Hematologic recovery followed copper supplementation, both initially and after relapse off copper therapy, while serum zinc levels remained high and the neurologic abnormalities only stabilized.
