Secondary operations are frequently required to complete the surgical phase of therapy in the era of breast conservation and sentinel lymph node biopsy
Secondary operations are frequently required to complete the surgical phase of therapy in the era of breast conservation and sentinel lymph node biopsy
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DOI：
10.1016/j.amjsurg.2004.01.003
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发表时间：
2004-05-01
影响因子：
3
通讯作者：
Carter, PL
中科院分区：
文献类型：
--
作者：
Mullenix, PS;Cuadrado, DG;Carter, PL
背景资料：对于大多数早期乳腺癌，保乳治疗（BCT）是一种与乳房切除术相当的肿瘤学和美容学上的首选替代方案。完成BCT治疗手术阶段所需的手术次数尚未得到广泛报道。方法：从我们的机构肿瘤登记处，我们回顾了1998年1月1日至2002年6月30日期间接受乳腺癌初次手术治疗的所有患者的记录。队列中有204名患者患有210例乳腺癌。这些癌症最初采用BCT（n = 150）或乳房切除术（改良根治性乳房切除术或全乳房切除术+前哨淋巴结活检）（n = 60）进行治疗。我们比较了各组中需要额外手术以获得清晰边缘、处理腋窝疾病或以其他方式完成手术治疗阶段的患者百分比。结果：51%的初次BCT治疗的患者需要额外手术，而乳房切除术组为12%（P
Background: Breast conservation therapy (BCT) is an oncologically equivalent and cosmetically preferable alternative to mastectomy for most early-stage breast cancers. The number of operations required to complete the surgical phase of therapy with BCT has not been widely reported.Methods: From our institutional tumor registry, we reviewed the records of all patients receiving primary surgical therapy for breast cancer from January 1, 1998, to June 30, 2002. There were 204 patients with 210 breast cancers in the cohort. These cancers were initially managed with either BCT (n = 150) or mastectomy (modified radical mastectomy or total mastectomy with sentinel lymph node biopsy) (n = 60). We compared the percentages of patients in each group who required additional surgeries to obtain clear margins, manage axillary disease, or otherwise complete the surgical phase of therapy. Patients with secondary surgery related to long-term local recurrence were excluded.Results: Fifty-one percent of patients initially managed with BCT required additional surgery compared with 12% in the mastectomy group (P