Asymmetric cooperativity in tandem hybridization of enantiomeric metal complex-tethered short fluorescent DNA probes.
Asymmetric cooperativity in tandem hybridization of enantiomeric metal complex-tethered short fluorescent DNA probes.
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DOI：
10.1039/b505632b
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发表时间：
2005-09
影响因子：
4.9
通讯作者：
Yusuke Kitamura;T. Ihara;K. Okada;Y. Tsujimura;Yoshinori Shirasaka;M. Tazaki;A. Jyo
中科院分区：
文献类型：
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作者：
Yusuke Kitamura;T. Ihara;K. Okada;Y. Tsujimura;Yoshinori Shirasaka;M. Tazaki;A. Jyo
将复合物[Ru(phen)(2)(dppz)](2+)(phen = 1,10-菲咯啉，dppz =联吡啶并[3,2-aratio2',3'-c]吩嗪)连接到短寡核苷酸的5'端形成缀合物，其Delta异构体在重复序列的识别过程中表现出高度的协同性，而Lambda异构体则没有。
The complex [Ru(phen)(2)(dppz)](2+)(phen = 1,10-phenanthroline, dppz = dipyrido[3,2-aratio2',3'-c]phenazine) was attached to the 5' end of a short oligonucleotide to form conjugates, the Delta-isomer of which showed a high cooperativity during the recognition of the repetitive sequence, while the Lambda-isomer did not.