Identifying the Impacts of Acne and the Use of Questionnaires to Detect These Impacts: A Systematic Literature Review.
Identifying the Impacts of Acne and the Use of Questionnaires to Detect These Impacts: A Systematic Literature Review.
复制标题
识别痤疮的影响以及使用调查问卷来检测这些影响：系统文献综述。
DOI：
10.1007/s40257-020-00564-6
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发表时间：
2021
影响因子：
7.3
通讯作者：
Eady,Anne
中科院分区：
文献类型：
--
作者：
Smith,Hayley;Layton,AlisonM;Thiboutot,Diane;Smith,Abbey;Whitehouse,Heather;Ghumra,Waseem;Verma,Meenakshi;Tan,Jerry;Jones,Georgina;Gilliland,Kathryn;Patel,Megha;Otchere,Elaine;Eady,Anne
背景痤疮（同义词：寻常痤疮）是全世界最常见的炎症性皮肤病。痤疮通常在青少年经历最大的身体和社会转变时影响他们，尽管流行率研究表明痤疮开始更早且持续时间更长，特别是在女性患者中。根据全球疾病负担研究，痤疮会造成重大的社会心理影响。因此，确定准确衡量疾病影响的机制非常重要。采用统一和标准化测量的方法现已被认为是任何临床评估的重要组成部分，并且可以更好地进行研究和荟萃分析之间的比较。 目标痤疮核心结果研究网络 (ACORN) 已确定相关领域作为临床研究中使用的核心结果测量集的一部分。其中之一是健康相关的生活质量 (HRQoL)。本系统综述的目的是提供信息，以帮助确定痤疮对患者最重要的影响。方法通过对文献的系统回顾，综合了有关痤疮影响的现有证据，并在 MEDLINE、EMBASE 和 PsychInfo 数据库中进行了搜索。结果我们确定了来自 58 个国家的 408 项研究，使用 138 种不同的仪器来检测痤疮的影响。五种最常用工具中的四种（皮肤科生活质量指数 [DLQI]、卡迪夫痤疮残疾指数 [CADI]、痤疮生活质量量表 [Acne-QoL]、医院焦虑和抑郁量表 [HADS] 和 Skindex-29）不能识别具体影响，而是量化痤疮对 HRQoL 的影响程度。其他研究使用开放式问题或量身定制的问卷来确定一个或多个影响。结论本综述为 ACORN（包括患者和医疗保健提供者）等团体未来努力开发一套用于临床试验的核心结果测量方法提供了丰富的数据源。
BackgroundAcne (syn: acne vulgaris) ranks as the most common inflammatory dermatosis treated worldwide. Acne typically affects adolescents at a time when they are undergoing maximum physical and social transitions, although prevalence studies suggest it is starting earlier and lasting longer, particularly in female patients. According to global burden of disease studies, acne causes significant psychosocial impact. Hence, identifying mechanisms to accurately measure the impact of the disease is important. Adopting an approach to harmonize and standardize measurements is now recognized as an essential part of any clinical evaluation and allows for better comparison across studies and meta-analyses.ObjectiveThe Acne Core Outcome Research Network (ACORN) has identified relevant domains as part of a core outcome set of measures for use in clinical studies. One of these is health-related quality of life (HRQoL). The aim of this systematic review was to provide information to inform the identification of the impacts most important to people with acne.MethodsA synthesis of available evidence on acne impacts was constructed from a systematic review of the literature, with searches conducted in the MEDLINE, EMBASE and PsychInfo databases.ResultsWe identified 408 studies from 58 countries using 138 different instruments to detect the impacts of acne. Four of the five most commonly used instruments (Dermatology Life Quality Index [DLQI], Cardiff Acne Disability Index [CADI], Acne Quality of Life scale [Acne-QoL], Hospital Anxiety and Depression Scale [HADS] and Skindex-29) do not identify specific impacts but rather quantify to what extent acne affects HRQoL. Other studies identified one or more impacts using open-ended questions or tailor-made questionnaires.ConclusionThis review serves as a rich data source for future efforts by groups such as ACORN (that include patients and health care providers) to develop a core set of outcome measurements for use in clinical trials.