A fatal rhino-cerebral zygomycosis in a young woman with latent diabetes mellitus and cerebral blood vessel agenesis
A fatal rhino-cerebral zygomycosis in a young woman with latent diabetes mellitus and cerebral blood vessel agenesis
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DOI：
10.3109/13693780903148361
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发表时间：
2010-03-01
期刊：
影响因子：
2.9
通讯作者：
Puntillo, F.
中科院分区：
文献类型：
--
作者：
Giglio, M.;Caggiano, G.;Puntillo, F.
鼻-脑真菌病是一种急性进行性真菌感染，常发生于糖尿病和酮症酸中毒患者。患者通常主诉位于面部、鼻部或眼眶区域的疼痛，随后突然失明和颅神经麻痹。早期诊断，纠正危险因素，及时手术切除和积极的抗真菌治疗是必要的挽救生命的治疗。下面的报告描述了一个致命的RCZ发生在一个明显健康的妇女与潜在的非失代偿性糖尿病和胎儿型后（FTP）环威利斯。
Rhino-cerebral zygomycosis (RCZ) is an acute rapidly progressive fungal infection usually occurring in patients with diabetes mellitus and ketoacidosis. Patients typically complain of pain located in the facial, nasal or orbital regions, followed by sudden blindness and cranial nerve palsy. Early diagnosis, correction of risk factors, prompt surgical removal and aggressive antifungal therapy are warranted as life-saving treatments. The following report describes a case of a lethal RCZ which occurred in an apparently healthy woman with latent non-decompensated diabetes mellitus and a fetal-type posterior (FTP) circle of Willis.