Composition (lean and fat tissue) of weight changes in adult Danes
Composition (lean and fat tissue) of weight changes in adult Danes
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DOI：
10.1093/ajcn/75.5.840
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发表时间：
2002-05-01
影响因子：
7.1
通讯作者：
Garby, L
中科院分区：
文献类型：
--
作者：
Heitmann, BL;Garby, L
背景资料：体重减轻可能与身体成分的不利变化有关，而随后的体重增加不会补偿这种变化。目的：我们研究了体重变化的组成与肥胖、先前的体重变化、减肥尝试和体力活动的关系。设计：丹麦MONICA（心血管疾病监测趋势）项目，这是一项关于体重和身体成分变化的纵向人群研究，1982-1983年、1987-1988年和1993-1994年进行了考试。共有1236名男性和1200名女性，年龄分别为35岁，45岁，55岁或65岁，在1987-1988年参加。在脂肪和无脂肪的质量的变化进行了测量bioelectricimpedance.Results：调整年龄相关的变化之前，无脂肪的质量弥补了41%的体重减轻和24%的体重增加的男性。在女性中，无脂肪质量的损失（35%）是增益（15%）的两倍多。调整后，重量a-游离质量的分数与脂肪分数损失时获得的分数没有显著差异。这些分数与年龄、肥胖和过去5年成功减肥尝试和体力活动中的体重变化无关。独立的年龄和程度的肥胖，体重的变化与更大的变化，在男性比在women.Conclusions：这些数据不支持的理论，体重减轻或体重循环可能会导致一个不利的身体成分，也没有提供一个生物学解释为什么长期减肥往往是不成功的。然而，体重变化的代谢和健康后果可能在男性和女性中有所不同。
Background: Weight loss may be associated with unfavorable changes in body composition not compensated for by subsequent weight gain.Objective: We examined the composition of weight change in relation to obesity, previous weight changes, weight-loss attempts, and physical activity.Design: Part of the Danish MONICA (Monitoring Trends in Cardiovascular Disease) project, this was a longitudinal population study of changes in weight and body composition, with examinations in 1982-1983, 1987-1988, and 1993-1994. A total of 1236 men and 1200 women aged 35, 45, 55, or 65 y in 1987-1988 participated. Changes in fat and fat-free mass were measured by bioelectrical impedance.Results: Before adjustment for age-related changes, fat-free mass made up 41% of weight lost and 24% of weight gained in men. In women, loss of fat-free mass (35%) was more than double that of gains (15%). After adjustment, the fractions of weight a-free mass were not significantly different from the gained as fat fractions lost. These fractions were independent of age, obesity, and weight changes in the previous 5 y successful weight-loss attempts and physical activity. Independent of age and degree of obesity, weight changes were associated with greater changes in fat-free mass in men than in women.Conclusions: These data do not support the theory that weight loss or weight cycling may lead to an unfavorable body composition, nor do they provide a biological explanation for why long-term weight loss is often unsuccessful. However, the metabolic and health consequences of weight change may differ in men and women.