Two iron-responsive promoter elements control expression of FOX1 in Chlamydomonas reinhardtii
Two iron-responsive promoter elements control expression of FOX1 in Chlamydomonas reinhardtii
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DOI：
10.1128/ec.00324-07
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发表时间：
2007-11-01
期刊：
影响因子：
--
通讯作者：
Eriksson, Mats
中科院分区：
文献类型：
--
作者：
Deng, Xiaodong;Eriksson, Mats
FOX 1编码一种铁缺乏诱导的铁氧化酶，参与高亲和力铁摄取系统。FOX 1启动子的突变分析鉴定了两个单独的铁响应元件，FeRE 1（CACACG）和FeRE 2（CACGCG），分别位于-87和-82之间以及-65和-60之间，并且两者都是在缺铁条件下诱导FOX 1表达所需的。
FOX1 encodes an iron deficiency-induced ferroxidase involved in a high-affinity iron uptake system. Mutagenesis analysis of the FOX1 promoter identified two separate iron-responsive elements, FeRE1 (CACACG) and FeRE2 (CACGCG), between positions -87 and -82 and between positions -65 and -60, respectively, and both are needed for induced FOX1 expression under conditions of iron deficiency.