EEG-defined subtypes of children with attention-deficit/hyperactivity disorder
EEG-defined subtypes of children with attention-deficit/hyperactivity disorder
复制标题
DOI：
10.1016/s1388-2457(01)00668-x
复制
发表时间：
2001-11-01
影响因子：
4.7
通讯作者：
Selikowitz, M
中科院分区：
文献类型：
--
作者：
Clarke, AR;Barry, RJ;Selikowitz, M
目的：本研究探讨了一个样本内的注意缺陷/多动障碍（ADHD）的组合类型的儿童的EEG集群的存在。方法：主题，包括184名男孩ADHD和40名年龄匹配的控制。在闭眼休息条件下从21个部位记录EEG，并进行傅立叶变换，以提供总功率估计值以及δ、θ、α和β波段的相对功率。以及θ/β比率。因子分析被用来分组的网站分为3个区域，包括前线。中央和后部区域。结果：ADHD儿童的脑电图有3个明显的特征：（1）慢波活动增加，快波活动减少; (b)增加高振幅θ与β活动的不足，和（c）一个过量的β group.Conclusions：这些结果表明，ADHD儿童不构成一个同质组在EEG剖面术语。这对研究EEG在ADHD诊断中的应用具有重要意义。努力旨在使用脑电图作为一种工具，从正常的ADHD儿童区分必须认识到ADHD人群中的变异性，如果这样的工具是有效的，可靠的临床实践。(C)2001爱思唯尔科学爱尔兰有限公司。保留所有权利。
Objectives: This study investigated the presence of EEG clusters within a sample of children with the combined type of attention-deficit/hyperactivity disorder (ADHD).Methods: Subject, consisted of 184 boys with ADHD and 40 age-matched controls. EEG was recorded from 21 sites during an eyes-closed resting condition and Fourier transformed to provide estimates for total power, and relative power in the delta, theta, alpha and beta bands. and for the theta/beta ratio. Factor analysis was used to group sites into 3 regions, covering frontal. central and posterior regions. These data were subjected to cluster analysis.Results: Three distinct EEG clusters of children with ADHD were found. These were characterized by (a) increased slow wave activity and deficiencies of fast wave. (b) increased high amplitude theta with deficiencies of beta activity, and (c) an excess beta group.Conclusions: These results indicate that children with ADHD do not constitute a homogenous group in EEG profile terms. This has important implications for studies of the utility of EEG in the diagnosis of ADHD. Efforts aimed at using EEG as a tool to discriminate ADHD children from normals must recognize the variability within the ADHD population if such a tool is to be valid and reliable in clinical practice. (C) 2001 Elsevier Science Ireland Ltd. All fights reserved.