How far can hydroxyl radicals travel? An electrochemical study based on a DNA mediated electron transfer process
How far can hydroxyl radicals travel? An electrochemical study based on a DNA mediated electron transfer process
复制标题
羟基自由基可以传播多远？
DOI：
10.1039/c1cc14699h
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发表时间：
2011-01-01
影响因子：
4.9
通讯作者：
Jia, Jianbo
中科院分区：
文献类型：
--
作者：
Guo, Qingqing;Yue, Qiaoli;Jia, Jianbo
利用光催化活性纳米粒子和DNA复合物修饰金电极，利用DNA介导的电子转移对碱基对堆积的敏感性，研究了光催化产生的羟基自由基（stecOH）对DNA氧化损伤的电荷转移效率的影响，并提出了一种读取stecOH有效扩散距离的电化学方法.
Using photocatalytic reactive nanoparticles and DNA composite modified gold electrodes, exploiting the sensitivity of DNA-mediated electron transfer to base pair stacking, we examined the effects of DNA oxidation damage by photocatalytically generated hydroxyl radicals (˙OH) on charge transfer efficiency and proposed an electrochemical technique to read the effective diffusing distance of ˙OH.