New directions in the epidemiology of uterine fibroids.
New directions in the epidemiology of uterine fibroids.
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DOI：
10.1055/s-0030-1251477
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发表时间：
2010-05
影响因子：
2.7
通讯作者：
Baird DD
中科院分区：
文献类型：
--
作者：
Laughlin SK;Schroeder JC;Baird DD
尽管子宫平滑肌瘤（肌瘤）几十年来一直是美国子宫切除术的主要适应症，但有关肌瘤患病率和危险因素的流行病学数据有限。鉴于肌瘤对激素的依赖性，大多数早期研究都集中在生殖或激素因素上。最近的分析已将这一重点扩展到其他领域。我们提供了先前未发表的关于生殖道感染之间关联的数据，这凸显了进行更详细研究的必要性。我们的综述表明，代谢、饮食、压力和环境因素也可能在肌瘤的发展中发挥作用。
Although uterine leiomyomata (fibroids) have been the leading indication for hysterectomy in the United States for decades, the epidemiologic data on fibroid prevalence and risk factors is limited. Given the hormonal dependence of fibroids, most earlier studies focused on reproductive or hormonal factors. Recent analyses have extended that focus to other areas. We present previously unpublished data on the association between reproductive tract infections that highlights the need for more detailed studies. Our review suggests that metabolic, dietary, stress, and environmental factors may also play a role in fibroid development.