Steric stabilization of thermally responsive N-isopropylacrylamide particles by poly(vinyl alcohol).
Steric stabilization of thermally responsive N-isopropylacrylamide particles by poly(vinyl alcohol).
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DOI：
10.1021/la1039128
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发表时间：
2010-12-07
期刊：
影响因子：
--
通讯作者：
Yates MZ
中科院分区：
文献类型：
--
作者：
Lee A;Tsai HY;Yates MZ
以聚乙烯醇（PVA）为空间稳定剂，在水中分散聚合交联聚N-异丙基丙烯酰胺（PNIPAM）。使用不同分子量和水解度的PVA进行一系列反应。以聚乙烯醇为稳定剂，在适当的条件下，制备出粒径均匀可控的PNIPAM粒子。通过测量不同离子强度的水性悬浮液中粒度随温度的变化来研究胶体稳定性。为了比较，平行的胶体稳定性的测量进行PNIPAM颗粒与低分子量离子表面活性剂合成。PVA在宽的温度和离子强度范围内提供胶体稳定性，而用离子表面活性剂产生的颗粒在水凝胶随温度升高而塌陷时在中等离子强度溶液中絮凝。实验结果和理论分析表明，空间稳定的PNIPAM粒子是由于PVA接枝到PNIPAM粒子表面而产生的。由PVA提供的增强的胶体稳定性允许温度响应性PNIPAM颗粒在静电稳定性无效的生理条件下使用。
Poly(vinyl alcohol) (PVA) was used as a steric stabilizer for the dispersion polymerization of crosslinked poly(N-isopropylacrylamide) (PNIPAM) in water. A series of reactions were carried out using PVA of varying molecular weight and degree of hydrolysis. Under appropriate conditions, PNIPAM particles of uniform and controllable size were produced using PVA as the stabilizer. The colloidal stability was investigated by measuring changes in particle size with temperature in aqueous suspensions of varying ionic strength. For comparison, parallel colloidal stability measurements were conducted on PNIPAM particles synthesized with low molecular weight ionic surfactants. The PVA provides colloidal stability over a wide range of temperature and ionic strength, whereas particles produced with ionic surfactants flocculate in moderate ionic strength solutions upon collapse of the hydrogel as temperature is increased. Experimental results and theoretical consideration indicate sterically stabilized PNIPAM particles resulted from grafting of PVA to the PNIPAM particle surface. The enhanced colloidal stability afforded by PVA allows the temperature responsive PNIPAM particles to be used under physiological conditions where electrostatic stability is ineffective.
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影响因子：
9.9
作者：
MCPHEE, W;TAM, KC;PELTON, R
通讯作者：
PELTON, R
影响因子：
5.5
作者：
OTAKE, K;INOMATA, H;SAITO, S
通讯作者：
SAITO, S
影响因子：
5.5
作者：
Gan, DJ;Lyon, LA
通讯作者：
Lyon, LA
DOI：
10.1016/0166-6622(86)80274-8
发表时间：
1986-10-01
期刊：
COLLOIDS AND SURFACES
影响因子：
--
作者：
PELTON, RH;CHIBANTE, P
通讯作者：
CHIBANTE, P
DOI：
10.1016/s0927-7757(99)00374-x
发表时间：
2000-01-30
影响因子：
5.2
作者：
Khan, AU;Briscoe, BJ;Luckham, PF
通讯作者：
Luckham, PF