A comparative case study of bowel cancer screening in the UK and Australia: evidence lost in translation?
A comparative case study of bowel cancer screening in the UK and Australia: evidence lost in translation?
复制标题
英国和澳大利亚肠癌筛查的比较案例研究：证据在翻译中丢失？
DOI：
10.1258/jms.2011.011066
复制
发表时间：
2011
影响因子：
2.9
通讯作者：
Trevena LJ
中科院分区：
文献类型：
--
作者：
Flitcroft KL;St John DJ;Howard K;Carter SM;Pignone MP;Salkeld GP;Trevena LJ
(I)根据七个主要特征记录英格兰、苏格兰、威尔士、北爱尔兰和澳大利亚肠癌筛查计划的现状，以及(Ii)探讨由于资金不足而造成的政策权衡。英国和澳大利亚。采用文献法和关键线人访谈分析的对比案例研究设计。对每个国家司法管辖区的7个主要方案特征的数据进行了整理：筛查频率、人口覆盖率、检测质量、方案模式、后续行动质量、结肠镜检查质量和数据收集质量。根据FOBT筛查文献和我们对每个方案的详细检查，编制了七个特征中每一个的最佳特征列表。每个国家为了节约成本和(或)管理有限而昂贵的资源，作出了不同的执行选择或取舍。这些权衡的总体结果可能是由于以下方面的妥协而导致方案有效性降低：筛查频率减少、目标年龄范围受到限制、使用不太准确的测试、故意设定较低的方案阳性率，或者对参与者重新测试造成更大的不便。资金不足迫使方案管理者做出权衡，这可能会破坏随机对照试验中实现的潜在净人口效益。这种政策妥协违反了循证做法的原则，而循证做法有赖于提供足够的资金。
(i) To document the current state of the English, Scottish, Welsh, Northern Irish and Australian bowel cancer screening programmes, according to seven key characteristics, and (ii) To explore the policy trade-offs resulting from inadequate funding. United Kingdom and Australia. A comparative case study design using document and key informant interview analysis. Data was collated for each national jurisdiction on seven key programme characteristics: screening frequency, population coverage, quality of test, programme model, quality of follow-up, quality of colonoscopy and quality of data collection. A list of optimal features for each of the seven characteristics was compiled, based on the FOBT screening literature and our detailed examination of each programme. Each country made different implementation choices or trade-offs intended to conserve costs and/or manage limited and expensive resources. The overall outcome of these trade-offs was probable lower programme effectiveness as a result of compromises such as reduced screening frequency, restricted target age range, the use of less accurate tests, the deliberate setting of low programme positivity rates, or increased inconvenience to participants from retesting. Insufficient funding has forced programme administrators to make trade-offs that may undermine the potential net population benefits achieved in randomized controlled trials. Such policy compromise contravenes the principle of evidence-based practice which is dependent on adequate funding being made available.
登录
查看更多内容
影响因子：
6.4
作者：
Launoy, GD;Bertrand, HJ;Caces, ER
通讯作者：
Caces, ER
影响因子：
2.9
作者：
Howard, K;Salkeld, G;Adelstein, BA
通讯作者：
Adelstein, BA
性别和抗拓扑异构酶 I 抗体在系统性硬化症中的影响
影响因子：
16.400
作者：
Rossella De Angelis
通讯作者：
Rossella De Angelis
影响因子：
24.5
作者：
Hol, L.;van Leerdam, M. E.;Kuipers, E. J.
通讯作者：
Kuipers, E. J.
影响因子：
24.5
作者：
Guittet, L.;Bouvier, V.;Launoy, G.
通讯作者：
Launoy, G.