Five-year stability in associations of health-related quality of life measures in community-dwelling older adults: the Rancho Bernardo Study

Five-year stability in associations of health-related quality of life measures in community-dwelling older adults: the Rancho Bernardo Study
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DOI:
10.1007/s11136-010-9700-y
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发表时间:
2010-11-01
影响因子:
3.5
通讯作者:
Barrett-Connor, Elizabeth
Barrett-Connor, Elizabeth
中科院分区:
医学2区
文献类型:
--
作者:
Der-Martirosian, Claudia;Kritz-Silverstein, Donna;Barrett-Connor, Elizabeth

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本研究在社区老年男性和女性中检验SF-12和SF-6D得分与较长的SF-36及其领域得分之间的五年稳定性。参与者为653名男性和917名女性,年龄在50岁及以上,他们完成了1995年和2000年的HRQOL邮寄调查。计算SF-36躯体(PCS)和精神(MCS)部分得分、领域得分、SF-12 PCS和MCS得分以及SF-6D得分。1995年男性平均年龄为68.2+/-A 10.7,女性为69.8+/-A 11.3。在1995年和2000年,男性在所有指标上的得分都明显更高(P<0.001)。SF-12PCS和MCS得分与SF-36PCS和MCS得分的性别相关系数在0.91~0.97之间(P‘s<0.000)。健康效用评分(SF-6D)与SF-36PCS和MCS评分也相关,但相关性较低,在0.61~0.79之间(P‘s<0.000)。按年龄分层比较SF-36PCS的5年变化分数显示,在所有四个年龄组(50-59岁、60-69岁、70-79岁、80岁以上)内,男性和女性的身体健康都显著下降,其中最大年龄组(80岁以上)的下降幅度最大。随着时间的推移,心理健康得分在年轻年龄组显示出显著的温和改善,但在70岁和80岁的男性和女性中下降。最年轻的男性和女性的SF-6D得分有所提高,但其他年龄组的平均变化得分下降。使用SF-12或SF-36工具都会得出类似的结论。然而,SF-6D和SF-36至少在一定程度上评估了HRQOL的不同基本方面。年龄和性别对HRQOL均有影响。
This study examines the five-year stability of the association of SF-12 and SF-6D scores with scores on the longer SF-36 and its domains in community-dwelling older men and women.Participants were 653 men and 917 women aged 50 and older who completed mailed surveys of HRQOL (1995, 2000). SF-36 physical (PCS) and mental (MCS) component scores, domain scores; SF-12 PCS and MCS scores; and SF-6D scores were computed.Average age in 1995 was 68.2 +/- A 10.7 for men and 69.8 +/- A 11.3 for women. In 1995 and 2000, men had significantly higher scores on all measures (P's < 0.001). Sex-specific Pearson correlations of SF-12 PCS and MCS scores with SF-36 PCS and MCS scores ranged from 0.91 to 0.97 (P's < 0.000). Health utility scores (SF-6D) were also associated with SF-36 PCS and MCS scores, but correlations were lower, ranging from 0.61 to 0.79 (P's < 0.000). Age-stratified comparisons of 5-year change scores for SF-36 PCS showed significant declines in physical health for both men and women within all four age-groups (50-59, 60-69, 70-79, 80+) with steepest declines in the oldest age-group (age 80+). Over time, mental health scores showed significant modest improvement in the younger age-groups but declines in men > 70 and women > 80 years. The SF-6D scores improved somewhat for the youngest men and women but mean change scores declined for the other age-groups.Similar conclusions would result using either instrument SF-12 or SF-36. However, SF-6D and SF-36 assess, at least in part, different underlying aspects of HRQOL. Both age and sex impact HRQOL.