World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia, Part 1: Update 2012 on the acute treatment of schizophrenia and the management of treatment resistance
World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia, Part 1: Update 2012 on the acute treatment of schizophrenia and the management of treatment resistance
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DOI：
10.3109/15622975.2012.696143
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发表时间：
2012-07-01
影响因子：
3.1
通讯作者：
Moeller, Hans-Juergen
中科院分区：
文献类型：
--
作者：
Hasan, Alkomiet;Falkai, Peter;Moeller, Hans-Juergen
这些更新的指南是基于2005年出版的世界生物精神病学学会联合会精神分裂症生物治疗指南第一版。在2012年修订版中，系统审查了所有与精神分裂症生物治疗相关的现有出版物，以进行循证更新。这些指南提供了临床和科学上有意义的循证实践建议，这些指南旨在供所有诊断和治疗精神分裂症患者的医生使用。基于这些指南的第一版，除了从国家治疗指南中提取数据外，还对MEDLINE/PUBMED数据库和科克伦图书馆进行了系统综述。对识别出的文献进行了疗效证据强度评价，然后将其分为6个证据等级（A-F; Bandelow et al. 2008 b，World J Biol Psychiatry 9：242）。更新指南的第一部分包括抗精神病药物及其副作用的一般描述、急性精神分裂症的生物治疗和难治性精神分裂症的管理。
These updated guidelines are based on a first edition of the World Federation of Societies of Biological Psychiatry Guidelines for Biological Treatment of Schizophrenia published in 2005. For this 2012 revision, all available publications pertaining to the biological treatment of schizophrenia were reviewed systematically to allow for an evidence-based update. These guidelines provide evidence-based practice recommendations that are clinically and scientifically meaningful and these guidelines are intended to be used by all physicians diagnosing and treating people suffering from schizophrenia. Based on the first version of these guidelines, a systematic review of the MEDLINE/PUBMED database and the Cochrane Library, in addition to data extraction from national treatment guidelines, has been performed for this update. The identified literature was evaluated with respect to the strength of evidence for its efficacy and then categorised into six levels of evidence (A-F; Bandelow et al. 2008b, World J Biol Psychiatry 9: 242). This first part of the updated guidelines covers the general descriptions of antipsychotics and their side effects, the biological treatment of acute schizophrenia and the management of treatment-resistant schizophrenia.