Opioid mediated suppressive effect of milk-derived lactoferrin on distress induced by maternal separation in rat pups
Opioid mediated suppressive effect of milk-derived lactoferrin on distress induced by maternal separation in rat pups
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DOI：
10.1016/s0006-8993(03)02941-x
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发表时间：
2003-07-25
期刊：
影响因子：
2.9
通讯作者：
Harada, E
中科院分区：
文献类型：
--
作者：
Takeuchi, T;Hayashida, KI;Harada, E
本研究评估了牛乳源性乳铁蛋白（bLf）对5- 18日龄大鼠幼仔由母体分离引起的痛苦活动的影响。给大鼠幼崽注射BSA（100 mg/kg，i. p.;对照）或bLf（100 mg/kg，i. p.）行为测试前30分钟。通过记录身体动作或超声波发声（USVs）来估计遇险活动。母婴分离5 min后，bLf显著升高（P
The present study assessed the effects of bovine milk-derived lactoferrin (bLf) on distress activities induced by maternal separation in 5- to 18-day-old rat pups. The rat pups were injected with BSA (100 mg/kg, i.p.; control) or bLf (100 mg/kg, i.p.) 30 min before the behavioral test. Distress activity was estimated by means of recording body movements or ultrasonic vocalizations (USVs). After 5 min of maternal separation, bLf significantly (P