Predictors of HIV Care Engagement, Antiretroviral Medication Adherence, and Viral Suppression Among People Living with HIV Infection in St. Petersburg, Russia.
Predictors of HIV Care Engagement, Antiretroviral Medication Adherence, and Viral Suppression Among People Living with HIV Infection in St. Petersburg, Russia.
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DOI：
10.1007/s10461-016-1638-9
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发表时间：
2018-03
影响因子：
4.4
通讯作者：
Musatov VB
中科院分区：
文献类型：
--
作者：
Amirkhanian YA;Kelly JA;DiFranceisco WJ;Kuznetsova AV;Tarima SS;Yakovlev AA;Musatov VB
俄罗斯已诊断出100多万人感染艾滋病毒，艾滋病毒护理接受率和病毒抑制率非常低。圣彼得堡的241名艾滋病毒阳性者通过社交网络登记，提供血液进行病毒载量测试，并完成了服药依从性、就绪性和自我效能、心理社会幸福感和药物使用的衡量标准。结果包括在过去的6个月中参加艾滋病毒护理预约，90%的抗逆转录病毒治疗依从性，以及无法检测到的病毒载量。26%的参与者最近没有预约护理，18%的人依从性不佳，56%的人有可检测到的病毒载量。饮酒一直预示着所有不利的健康后果。没有最近的护理访问还与单身以及过去一个月注射毒品的频率较高有关。服药依从性差还会导致服药自我效能感降低和焦虑降低。可检测到的病毒载量还与年龄较小有关。改善俄罗斯艾滋病毒护理的综合干预措施必须解决药物滥用、焦虑和服药自我效能问题。
Over 1 million HIV infections have been diagnosed in Russia, and HIV care uptake and viral suppression are very low. 241 HIV-positive individuals in St. Petersburg were enrolled through social networks, provided blood for viral load testing, and completed measures of medication-taking adherence, readiness, and self-efficacy; psychosocial well-being; and substance use. Outcomes included attending an HIV care appointment in the past 6 months, >90% ART adherence, and undetectable viral load. 26% of participants had no recent care appointment, 18% had suboptimal adherence, and 56% had detectable viral load. Alcohol use consistently predicted all adverse health outcomes. Having no recent care visit was additionally associated with being single and greater past-month drug injection frequency. Poor adherence was additionally predicted by lower medication-taking self-efficacy and lower anxiety. Detectable viral load was additionally related to younger age. Comprehensive interventions to improve HIV care in Russia must address substance abuse, anxiety, and medication-taking self-efficacy.