Dynamic changes and spatial correlation of EEG activities during cold pressor test in man
Dynamic changes and spatial correlation of EEG activities during cold pressor test in man
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DOI：
10.1016/s0361-9230(01)00763-8
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发表时间：
2002-03-15
影响因子：
3.8
通讯作者：
Chen, ACN
中科院分区：
文献类型：
--
作者：
Chang, PF;Arendt-Nielsen, L;Chen, ACN
为探讨强直性冷痛对人体的影响，对15名健康青年男性进行了冷加压试验（CPT）前、中、后的疼痛强度、痛苦程度、皮温和连续脑电图记录。采集的脑电图（EEG）数据进行了分析，在四个方面：（1）比较EEG的地形图和功率谱的基线，CPT，和CPT后;（2）动态EEG的变化在CPT期间;（3）相关性的EEG活动在孤立的焦点最大跨三个实验阶段;（4）空间相关性的EEG功率之间的焦点网站在CPT期间。与基线相比，CPT引起的脑电地形图和功率谱的显着差异，表现出以下特点。(A)三角洲和θ活动增加，在F8的最大额区。(B)α活性在头部后部降低，在POz处达到最大值。(C)在周边双颞区的β活动增加。(D)CPT发作后即刻α活性下降，β活性上升，而δ活性的上升则呈现一个相对平缓的过程。(E)在各个阶段，在F8的δ屈光度和POz的α-1屈光度中观察到显著的个体一致性。(F)两个独立的空间集群的EEG激活，额颞三角洲-θ-β活动和后顶叶α活动出现在CPT。这一新的证据和CPT的详细EEG效应可能会增强我们对大脑处理强直性伤害性信息的动力学的理解。α波降低可能反映了伤害性输入的注意加工过程，δ/θ/β波激活可能与大脑的动机调制有关。(C)2002年爱思唯尔科技有限公司
To explore the effects of tonic cold pain in man, the pain rating (intensity and distress), skin temperature, and continuous EEG recording were conducted before, during, and after cold pressor test (CPT) in 15 young healthy males. The acquired electroencephalogram (EEG) data was analysed in four ways: (1) comparison of EEG topographic patterns and power spectra across baseline, CPT, and post-CPT; (2) dynamic EEG changes during CPT; (3) correlation of EEG activities at the isolated focal maxima across the three experimental stages; and (4) spatial correlation of EEG powers among the focal sites during CPT. Compared to baseline, CPT induced significant differences in EEG topographic patterns and power spectra, which showed the following characteristics. (A) The delta and theta activities increased in frontal areas with maxima at F8. (B) The alpha activities decreased in the posterior part of the head with maxima at POz. (C) The beta activities increased in the peripheral bi-temporal regions. (D) The decrease of alpha and increase of beta activities occurred immediately after the onset of CPT, but the increase of delta activity showed a relatively gradual process. (E) Individual consistency was significantly observed in delta power at F8 and alpha-1 power at POz across the stages. (F) Two independent spatial clusters of EEG activation, fronto-temporal delta-theta-beta activities and posterior parietal alpha activities emerged during CPT. This new evidence and the detailed EEG effects in CPT may enhance our understanding of the dynamics in cerebral processing of tonic noxious information. Alpha reduction may reflect the attention processing in nociceptive input, and the delta/theta/beta activation may be related to the motivational modulation of the brain. (C) 2002 Elsevier Science Inc.