Transient circadian internal desynchronization after light-dark phase shift in monkeys.
Transient circadian internal desynchronization after light-dark phase shift in monkeys.
复制标题
猴子明暗相移后短暂的昼夜节律内部不同步。
作者：
M. Moore;D. Kass;J. Herd
在四个有意识的椅子上驯化的松鼠猴（Saimiri sciureus）研究与灯光（600 lx）从0800至2000小时每天（LD 12：12），突出的24小时节律的喂养，饮水，活动，体温，尿钾，钠，和水的排泄。当猴子进行36小时的黑暗，然后36小时的光每个变量表现出昼夜节律，这是不是被动依赖于光暗周期。当24 h的光暗周期突然延迟8 h后，所有的节律都与新的光暗周期相重叠，说明光暗周期是一种有效的授时因子。然而，进食、饮水、活动和体温的节律在大约2天内完成90%的恢复，而排尿节律的90%恢复需要大约5天。这些结果表明，S。sciureus可以由几个自发振荡单元组成，这些自发振荡单元在环境时间线索的扰动期间可以变得瞬时解耦。
In four conscious chair-acclimatized squirrel monkeys (Saimiri sciureus) studied with lights on (600 lx) from 0800 to 2000 h daily (LD 12:12), prominent 24-h rhythms in feeding, drinking, activity, body temperature, and urinary potassium, sodium, and water excretion were seen. When the monkeys were subjected to 36 h of darkness followed by 36 h of light each variable demonstrated a circadian rhythm which was not passively dependent on the light-dark cycle. After the 24-h light-dark cycle was abruptly phase-delayed by 8 h, all the rhythms resynchronized with the new light-dark cycle phase, demonstrating that light-dark cycles are an effective zeitgeber. However, the resynchronization of the rhythms of feeding, drinking, activity, and body temperature was 90% complete within approximately 2 days while the 90% resynchronization of the urinary rhythms took approximately 5 days. These results suggest that the circadian timing system in S. sciureus may consist of several spontaneously oscillating units which can become transiently uncoupled during pertubations of environmental time cues.