Synaptotagmin: fusogenic role for calcium sensor?
Synaptotagmin: fusogenic role for calcium sensor?
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DOI:
10.1038/nsmb0406-301
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发表时间:
2006-04
期刊:
影响因子:
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通讯作者:
J. Zimmerberg;S. A. Akimov;V. Frolov
中科院分区:
文献类型:
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作者:
J. Zimmerberg;S. A. Akimov;V. Frolov
Two recent studies focusing on synaptotagmin-1's role in synaptic vesicle fusion suggest that it may be key in bringing vesicle and target membranes together and in promoting SNARE assembly. The highly positive electrostatic potential of the synaptotagmin surface could catalyze fusion.