A combination of chlorambucil, vinblastine, procarbazine and prednisolone for treatment of Hodgkin's disease.

A combination of chlorambucil, vinblastine, procarbazine and prednisolone for treatment of Hodgkin's disease.
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DOI:
10.1038/bjc.1977.187
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发表时间:
1977-08
影响因子:
8.8
通讯作者:
Austin, D E
Austin, D E
中科院分区:
医学1区
文献类型:
--
作者:
McElwain, T J;Toy, J;Smith, E;Peckham, M J;Austin, D E

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70例霍奇金氏病患者用氯氨丁苯、长春花碱、丙卡巴肼和强的松龙(Ch1VPP)联合治疗。75%-7%的完全缓解率与其他组合的完全缓解率相比很好。这种组合无毒,易于服用,可以安全地给门诊患者服用。它的主要优点是,与含氮芥末的混合物相比,它对患者的困扰要小得多。
Seventy patients with Hodgkin's disease have been treated with a combination of chlorambucil, vinblastine, procarbazine and prednisolone (Ch1VPP). The complete remission rate of 75-7% compares well with that produced by other combinations. The combination is non-toxic, easily administered and can be given safely to outpatients. Its main advantage is that it is far less upsetting to patients than combinations containing nitrogen mustard.