Physical Activity Trajectories Preceding Incident Heart Failure: A Proof-of-Concept Study.
Physical Activity Trajectories Preceding Incident Heart Failure: A Proof-of-Concept Study.
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心力衰竭发生前的体力活动轨迹：概念验证研究。
DOI：
10.1016/j.jchf.2023.09.006
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发表时间：
2024
期刊：
影响因子：
--
通讯作者：
Brittain,EvanL
中科院分区：
文献类型：
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作者：
Hughes,AndrewM;Annis,Jeffrey;Master,Hiral;Perry,AndrewS;Stevenson,LynneW;Shah,Ravi;Brittain,EvanL
运动耐量降低是心力衰竭（HF）患者的标志性症状。1早期的研究通过自我报告的问卷调查或使用研究级设备的单一短暂监测期来评估身体活动水平（帕尔斯），并且通常在多年后进行结果评估。2因此，在新诊断为HF之前，对PAL趋势知之甚少。通过利用AoURP（All of Us Research Program），我们的初步研究旨在调查在患有心脏合并症的高风险患者中监测Fitbit设备的PAL趋势是否具有潜在的临床价值。（第6版），以分析2013年10月20日至2021年12月2日期间与电子健康记录（EHR）关联的Fitbit设备的数据。之前已经描述了AoURP和Fitbit数据。3简而言之，Fitbit数据包括平均每日步数和每天分级强度的平均分钟数。我们分析了相当活跃和非常活跃的时间的综合指标，以反映中度到剧烈的身体活动。主要结局是新诊断为HF，定义为1例住院患者或2例门诊患者国际疾病分类
Decreased exercise tolerance is a hallmark symptom of patients with heart failure (HF). 1 Earlier studies assessed physical activity levels (PALs) with selfreported questionnaires or a single brief monitoring period by using research grade devices, and the assessment of outcomes typically occurred many years later. 2 As such, little is known about the PAL trends preceding a new diagnosis of HF. By leveraging the AoURP (All of Us Research Program), our pilot study aimed to investigate whether there is potential clinical value to monitor PAL trends from Fitbit devices in high-risk patients with cardiac comorbidities.The study used the Controlled Tier Dataset (version 6) from the AoURP to analyze data from Fitbit devices linked to the electronic health record (EHR) from October 20, 2013 to December 2, 2021. The AoURP and Fitbit data have been described previously. 3 Briefly, Fitbit data consisted of average daily steps and average minutes of graded intensity per day. We analyzed a combined metric of fairly active and very active minutes to reflect moderate to vigorous physical activity. The primary outcome was a new diagnosis of HF, defined as 1 inpatient or 2 outpatient International Classification of Diseases