WAT do you NO? Addressing obesity-related cardiometabolic dysfunction.

WAT do you NO? Addressing obesity-related cardiometabolic dysfunction.
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你不做什么？

DOI：
10.1113/jp281276
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发表时间：
2021
期刊：
The Journal of physiology
影响因子：
--
通讯作者：
Clayton,ZacharyS
Clayton,ZacharyS
中科院分区：
--
文献类型：
--
作者：
Mahoney,SophiaA;Ikoba,AkpevweP;Rossman,MatthewJ;Clayton,ZacharyS

文献摘要

相似文献

炎症和氧化应激是共生的，相互促进的；因此，肥胖相关的炎症也可以驱动WAT的氧化应激。这些变化可能在一定程度上与肥胖相关的一氧化氮（NO）生物利用度降低有关，这与动脉功能受损和心血管疾病（CVD）风险增加有关。解决肥胖相关的心脏代谢功能障碍。[文章节选]
Inflammation and oxidative stress are symbiotic and mutually reinforcing; thus, obesity-related inflammation can also drive oxidative stress in WAT. These changes may be responsible, in part, for obesity-related reductions in nitric oxide (NO) bioavailability, which is linked to impaired arterial function and increased cardiovascular disease (CVD) risk. Addressing obesity-related cardiometabolic dysfunction.[Extracted from the article]