Clinical characteristics of patients with labyrinthine fistulae caused by middle ear cholesteatoma
Clinical characteristics of patients with labyrinthine fistulae caused by middle ear cholesteatoma
复制标题
中耳胆脂瘤致迷路瘘患者的临床特征
DOI：
10.3760/cma.j.issn.0366-6999.20123026
复制
发表时间：
2013-06
影响因子：
6.1
通讯作者：
Li Yi-ke
中科院分区：
文献类型：
--
作者：
Chi Fang-lu;Han Zhao;Huang Yi-bo;Li Yi-ke
背景中耳乳突瘘管（LF）是一种常见的临床并发症，主要由中耳乳突瘤引起。中耳乳突瘤所致不同程度LF的存在是否加重了感觉神经性听力损失（NSHL），LF引起的听力损失程度如何，目前仍存在争议。本研究旨在探讨中耳炎患者LF程度与年龄分布、病程及听力损失程度的关系。方法回顾性分析143例中耳乳突瘤患者的临床资料。78例LF患者根据迷路破坏程度分为三种类型。随机选择65例无LF的患者作为对照。然后，我们比较了中耳乳突瘤引起的中耳瘘管与非中耳瘘管的临床特征。结果与无LF的患者相比，有LF的患者年龄较大，病程较长。无论有无LF，高频听力损失都很严重。内耳损害程度与迷路破坏程度相关，迷路破坏越严重，内耳损害相关症状越严重。结论对此类非手术治疗的患者应尽早手术治疗。
Background Labyrinthine fistula (LF) is a very common clinical complication mainly caused by middle ear cholesteatoma. Whether the presence of different degree LF caused by middle ear cholesteatoma aggravates neurosensory hearing loss (NSHL) and what is the degree of the hearing loss caused by LF were still under controversial. This study aimed to investigate whether the LF degree is correlative with the age distribution, disease duration and hearing loss degree for cholesteatomatous patients. Methods The files of 143 patients with middle ear cholesteatoma were selected and reviewed in a retrospective study. Seventy‐eight patients with LF were divided into three types according to the degree of destruction of labyrinth. Sixty‐five patients without LF were randomly chosen for control. Then, we compared the clinical characteristics of patients with or without labyrinthine fistulae caused by middle ear cholesteatoma. Results According to the study, cholesteatomatous patients with LF were older and suffered longer disease duration than those without LF. Hearing loss is severe with high frequencies both in patients with and without LF. Moreover, inner ear impairment is correlative with the degree of destruction in labyrinth, and more severe destruction in labyrinth follow the more severe symptoms correlative with inner ear impairment. Conclusion Surgical intervention should be performed as early as possible for these cholesteatomatous patients.
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影响因子：
0.4
作者：
A. Faramarzi;S. Heydari;M. Rusta
通讯作者：
A. Faramarzi;S. Heydari;M. Rusta
影响因子：
1.4
作者：
Linstrom, CJ;Silverman, CA;Meiteles, LZ
通讯作者：
Meiteles, LZ
DOI：
10.1016/s0196-0709(00)80072-1
发表时间：
2000-01-01
期刊：
AMERICAN JOURNAL OF OTOLOGY
影响因子：
--
作者：
Gersdorff, MCH;Nouwen, J;Bosch, P
通讯作者：
Bosch, P
DOI：
--
发表时间：
1997-11
期刊：
The American journal of otology
影响因子：
--
作者：
G. Magliulo;G. Terranova;S. Varacalli;C. Sepe
通讯作者：
G. Magliulo;G. Terranova;S. Varacalli;C. Sepe
影响因子：
1.4
作者：
L. Ruedi
通讯作者：
L. Ruedi