On Pilot Massive COVID-19 Testing by Antigen Tests in Europe. Case Study: Slovakia.

On Pilot Massive COVID-19 Testing by Antigen Tests in Europe. Case Study: Slovakia.
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DOI:
10.3390/idr13010007
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发表时间:
2021-01-07
影响因子:
3.2
通讯作者:
Durica M
Durica M
中科院分区:
其他
文献类型:
--
作者:
Frnda J;Durica M

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本文概述了斯洛伐克几乎所有人口通过抗原检测进行的大规模COVID-19检测。我们将重点放在两个测试轮交付的结果上,并分析了这种类型的测试的优点和缺点。我们准备了数学模型来严格检查检测的有效性,我们还估计了被抗原检测标记为阳性的人感染的潜在病人的数量。我们的计算证明,在热点地区进行抗原检测可以显着拉平每日新报告病例的曲线,但在低风险地区,这种检测的好处值得怀疑。对于感染率较低的地区,由于国家卫生部门尚未对RT-PCR检测结果进行验证,我们只能估计真阳性和假阳性病例的比例。因此,本工作可以作为欧洲首次在全国范围内进行抗原检测的介绍性研究。
This paper provides a summary of mass COVID-19 testing of almost the entire population in Slovakia by antigen tests. We focused on the results delivered by two testing rounds and analyzed the benefits and weaknesses of such type of testing. We prepared mathematical models to critically examine the effectiveness of the testing, and we also estimated the number of potentially sick people that would become infected by those marked as positives by antigen tests. Our calculations have proven that antigen testing in hotspots can flatten the curve of daily newly reported cases significantly, but in regions with low-risk of COVID-19, the benefit of such testing is questionable. As for the regions with low infection rates, we could only estimate the proportion of true and false-positive cases because the national health authority had not validated the results by RT–PCR tests. Therefore, this work can serve as an introductory study on the first nationwide testing by antigen tests in Europe.