Pancreatic cancer chemoprevention by phytochemicals.

Pancreatic cancer chemoprevention by phytochemicals.
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DOI:
10.1016/j.canlet.2012.10.020
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发表时间:
2013-06-28
期刊:
影响因子:
9.7
通讯作者:
Srivastava, Sanjay K.
Srivastava, Sanjay K.
中科院分区:
医学1区
文献类型:
--
作者:
Boreddy, Srinivas Reddy;Srivastava, Sanjay K.

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胰腺癌是美国癌症相关死亡的第四大原因。尽管手术、放疗和化疗等当前治疗方式取得了进展,但患者的平均五年生存率仍然低于 5%。最近,天然来源的化合物作为抗癌剂受到广泛关注。过去几十年发表的许多流行病学研究表明,食用蔬菜、水果或植物衍生产品与降低癌症发病率之间存在很强的相关性。本综述重点关注各种天然产物的潜在抗肿瘤作用。
Pancreatic cancer is fourth leading cause of cancer-related deaths in the United States of America. In spite of recent advances in the current therapeutic modalities such as surgery, radiation and chemotherapy patients, the average five year survival rate remains still less than 5%. Recently, compounds from natural sources receive ample of attention as anti-cancer agents. Many epidemiological studies published over the past few decades provide a strong correlation between consumption of vegetables, fruits or plant derived products and reduced incidence of cancer. The present review focuses on the potential antitumor effects of various natural products.
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