A Retrospective Study of Canine Idiopathic Epilepsy in Referral Centers in Japan
A Retrospective Study of Canine Idiopathic Epilepsy in Referral Centers in Japan
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日本转诊中心犬特发性癫痫的回顾性研究
DOI：
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
Hinako Yamazoe
中科院分区：
文献类型：
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作者：
G. Togawa;M. Saito;Itsuki Uebayashi;Y. Ohnishi;Hinako Yamazoe
特发性癫痫（Idiopathic epilepsy，IE）是犬最常见的神经系统疾病之一。本研究的目的是描述日本IE犬的临床数据，并寻找IE的诱发因素进行进一步研究。回顾性分析了2013年4月至2016年3月期间在2个转诊中心诊断为IE的犬的病历和临床信息。根据国际兽医癫痫工作组发表的共识声明进行。共使用了70只犬，中位（范围）体重为5.15（1.85-79.85）kg，首次癫痫发作时的年龄为4.2（0.3-11.8）岁。44只犬为雄性，26只为雌性。玩具贵宾犬在本研究中的代表性过高，表明该品种可能易患IE，并将成为基因研究的候选者，以阐明犬IE的病因。
Idiopathic epilepsy (IE) is one of the most common neurologic disorder in dogs. The aim of this study was to describe the clinical data of dogs with IE in Japan and to search for predisposing factors of IE for further investigation. Medical records and clinical information of dogs diagnosed with IE at 2 referral centers between April 2013 and March 2016 were retrospectively reviewed. It was conducted according to the consensus statement published by International Veterinary Epilepsy Task Force. A total of 70 dogs were used with a median (range) weight of 5.15 (1.85–79.85) kg and age at initial epileptic seizure onset of 4.2 (0.3–11.8) years. Fortyfour dogs were male, and 26 were female. Toy Poodles were over-represented in the present study indicating that this breed may be predisposed to IE and would be a candidate for gene study to elucidate the cause of IE in dogs.