Factors associated with the use of over-the-counter medications in cases of acute gastroenteritis in Hamilton, Ontario
Factors associated with the use of over-the-counter medications in cases of acute gastroenteritis in Hamilton, Ontario
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DOI：
10.1007/bf03405234
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发表时间：
2006-11-01
影响因子：
4.3
通讯作者：
Edge, Victoria L.
中科院分区：
文献类型：
--
作者：
Frosst, Gillian O.;Majowicz, Shannon E.;Edge, Victoria L.
背景：监测非处方（OTC）药品销售可以提供一种准确、可靠的方法来观察趋势并发现社区健康状况的异常。本研究评估了与急性胃肠炎（GE）患者使用非处方抗恶心药（AN）、抗腹泻药（AD）和补液疗法（RT）相关的人口统计学和症状因素。方法：对351例自报急性GE的人群电话调查资料进行分析。关注的四个结果是使用OTC药物1)AD, 2) an, 3) RT，以及4)至少使用三种药物中的一种。评估了每个感兴趣的因素与使用OTC治疗之间的关系。结果：在351例病例中，110例（31%）使用了至少一种OTC AD、AN或RT治疗他们的疾病。最显著的相关因素是主要症状组：同时伴有呕吐和腹泻的病例使用三种非处方药中至少一种的可能性是仅伴有呕吐或腹泻的病例的3.6倍。与使用至少一种OTC相关的其他因素是女性（OR=1.97）， 10-14岁（OR=11.22），以及在发病前28天内使用抗酸药（OR=2.31）。结论：本研究首次发表了对社区GE病例使用非处方药相关因素的评估。那些使用OTC药物治疗疾病的人似乎与那些不使用OTC药物的人有所不同。这些信息可为卫生官员提供信息，并有助于开展以药物为基础的综合征监测。
Background: Monitoring over-the-counter (OTC) medication sales may provide an accurate, reliable way to observe trends and detect aberrations in community health status. This study assessed demographic and symptomatic factors associated with the use of OTC anti-nauseants (AN), anti-diarrheals (AD), and rehydration therapies (RT) in cases of acute gastroenteritis (GE).Methods: Data on 351 cases of self-reported, acute GE obtained from a population-based telephone survey were analyzed. The four outcomes of interest were use of an OTC 1) AD, 2) AN, 3) RT, and 4) use of at least one of the three. The association between each factor of interest and the use of OTC treatments was assessed.Results: Of the 351 cases, 110 (31%) used at least one OTC AD, AN, or RT for their illness. The most significantly associated factor was primary symptom group: cases with both vomiting and diarrhea were 3.6 times more likely to use at least one of the three OTC medications than cases with either vomiting or diarrhea only. Other factors associated with the use of at least one OTC were being female (OR=1.97), being 10-14 years of age (OR=11.22), and use of antacids in the 28 days prior to illness (OR=2.31).Conclusion: This study provides the first published assessment of factors associated with the use of OTC medications by community cases of GE. Those who use OTC medications for their illness appear to differ from those who do not. This information can inform health officials, and aid development of pharmacy-based syndromic surveillance.