Prevalence of amblyopia or strabismus in asian and non-Hispanic white preschool children: multi-ethnic pediatric eye disease study.
Prevalence of amblyopia or strabismus in asian and non-Hispanic white preschool children: multi-ethnic pediatric eye disease study.
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DOI：
10.1016/j.ophtha.2013.03.001
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发表时间：
2013-10
期刊：
影响因子：
13.7
通讯作者：
Multi-Ethnic Pediatric Eye Disease Study Group
中科院分区：
文献类型：
--
作者：
McKean-Cowdin R;Cotter SA;Tarczy-Hornoch K;Wen G;Kim J;Borchert M;Varma R;Multi-Ethnic Pediatric Eye Disease Study Group
确定30 - 72个月亚洲和非西班牙裔白色儿童弱视的年龄和种族特异性患病率以及6 - 72个月儿童斜视的年龄和种族特异性患病率。横截面调查。在加州的洛杉矶和滨江县，确定了一个以人群为基础的6至72个月的多种族儿童样本，以评估眼部疾病的患病率。对80%符合条件的儿童进行了全面的眼科检查和门诊访谈。检查包括评估6至72个月儿童的眼球排列、屈光不正和眼部结构，以及确定30至72个月儿童的视标视力（VA）。6至72个月大斜视和30至72个月大视力缺陷和弱视风险因素的受试者比例与弱视的研究定义一致。在3.55%（95%置信区间[CI]，2.68-4.60）的亚裔儿童和3.24%（95% CI，2.40-4.26）的非西班牙裔白色儿童中发现斜视，在两个种族/种族组中，6至72个月的每个后续年龄组的患病率更高（分别为P=0.0003和0.02）。在亚洲和非西班牙裔白色儿童中检测到1.81%（95% CI，1.06-2.89）的弱视;在非西班牙裔白色儿童中，弱视的患病率在随后的各年龄组中均较高（P=0.01），但在亚洲儿童中未显示出显著趋势（P=0.30）。斜视的患病率在亚洲和非西班牙裔白色儿童中相似，在6至72个月大的儿童中更高。亚洲和非西班牙裔白色儿童的弱视患病率相同;年龄较大的非西班牙裔白色儿童的患病率似乎较高，但亚洲儿童的患病率相对稳定。这些发现可能有助于临床医生更好地了解斜视和弱视的模式，并可能为学龄前视力筛查计划提供信息。
To determine the age- and race-specific prevalence of amblyopia in Asian and non-Hispanic white children aged 30 to 72 months and of strabismus in children aged 6 to 72 months. Cross-sectional survey. A population-based, multiethnic sample of children aged 6 to 72 months was identified in Los Angeles and Riverside counties in California to evaluate the prevalence of ocular conditions. A comprehensive eye examination and in-clinic interview were conducted with 80% of eligible children. The examination included evaluation of ocular alignment, refractive error, and ocular structures in children aged 6 to 72 months, as well as a determination of optotype visual acuity (VA) in children aged 30 to 72 months. The proportion of 6- to 72-month-old participants with strabismus and 30- to 72-month-olds with optotype VA deficits and amblyopia risk factors consistent with study definitions of amblyopia. Strabismus was found in 3.55% (95% confidence interval [CI], 2.68–4.60) of Asian children and 3.24% (95% CI, 2.40–4.26) of non-Hispanic white children, with a higher prevalence with each subsequent older age category from 6 to 72 months in both racial/ethnic groups (P=0.0003 and 0.02, respectively). Amblyopia was detected in 1.81% (95% CI, 1.06–2.89) of Asian and non-Hispanic white children; the prevalence of amblyopia was higher for each subsequent older age category among non-Hispanic white children (P=0.01) but showed no significant trend among Asian children (P=0.30). The prevalence of strabismus was similar in Asian and non-Hispanic white children and was found to be higher among older children from 6 to 72 months. The prevalence of amblyopia was the same in Asian and non-Hispanic white children; prevalence seemed to be higher among older non-Hispanic white children but was relatively stable by age in Asian children. These findings may help clinicians to better understand the patterns of strabismus and amblyopia and potentially inform planning for preschool vision screening programs.