An update on the comparisons of mortality outcomes of hemodialysis and peritoneal dialysis patients.

An update on the comparisons of mortality outcomes of hemodialysis and peritoneal dialysis patients.
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DOI:
10.1016/j.semnephrol.2011.01.004
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发表时间:
2011-03
影响因子:
3.3
通讯作者:
Mehrotra, Rajnish
Mehrotra, Rajnish
中科院分区:
医学2区
文献类型:
--
作者:
Chiu, Yi-Wen;Jiwakanon, Sirin;Lukowsky, Lilia;Duong, Uyen;Kalantar-Zadeh, Kamyar;Mehrotra, Rajnish

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透析患者的数量持续增长。在世界上许多地方,腹膜透析(PD)是一种较便宜的治疗方式。然而,人们一直质疑PD患者是否能获得与血液透析(HD)一样好的长期预后。这种怀疑助长了对中心HD和PD患者治疗结果的持续比较,这些比较使用的数据来自国家登记处或前瞻性队列研究。当治疗分配非随机时,比较两种治疗的结果存在主要挑战。此外,许多跨模式比较包括了在20世纪90年代开始透析治疗的患者。在世界上的许多地方,PD结果的改善已经超过了中心HD的改善。因此,毫不奇怪,几乎所有来自世界各地的观察性研究一致表明,HD和PD患者的长期生存率非常相似。这些研究支持更多地使用PD治疗终末期肾脏疾病——反过来,这可以允许更多的患者接受长期透析的任何预算分配。
The number of dialysis patients continues to grow. In many parts of the world, peritoneal dialysis (PD) is a less expensive form of treatment. However, it has been questioned whether patients treated with PD can have as good a long-term outcome as that achieved with hemodialysis (HD). This skepticism has fueled ongoing comparisons of outcomes of patients treated with in-center HD and PD using data from national registries, or prospective cohort studies. There are major challenges in comparing outcomes with two therapies when the treatment assignment is non-random. Furthermore, many of the inter-modality comparisons include patients who started dialysis therapy in the 1990s. In many parts of the world, improvements in PD outcome have outpaced those seen with in-center HD. It is not surprising, then, that virtually all the recent observational studies from different parts of the world consistently show that long-term survival of HD and PD patients is remarkably similar. These studies support the case for a greater use of PD for the treatment of end-stage renal disease – this, in turn, could allow more patients to be treated for any given budgetary allocation to long-term dialysis.
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