High Salt Intake Independent Risk Factor for Obesity?
High Salt Intake Independent Risk Factor for Obesity?
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DOI：
10.1161/hypertensionaha.115.05948
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发表时间：
2015-10-01
期刊：
影响因子：
8.3
通讯作者：
MacGregor, Graham A.
中科院分区：
文献类型：
--
作者：
Ma, Yuan;He, Feng J.;MacGregor, Graham A.
高盐摄入是导致血压升高的主要原因，从而导致心血管疾病。最近，研究表明，高盐摄入量与含糖饮料消费增加肥胖风险相关。越来越多的证据也表明存在直接联系。我们的研究旨在确定盐摄入量与肥胖之间是否存在独立于能量摄入的直接关联。我们分析了滚动横断面研究——2008/2009年至2011/2012年英国国家饮食和营养调查的数据。我们纳入了 458 名儿童（52% 男孩；年龄，10 +/- 4 岁）和 785 名成人（47% 男性；年龄，49 +/- 17 岁），他们进行了完整的 24 小时尿液收集。能量摄入量是根据 4 天的日记计算的，并通过戈德堡方法评估误报。结果表明，通过 24 小时尿钠测量，超重和肥胖个体的盐摄入量较高。盐摄入量每天增加 1 克，儿童肥胖风险增加 28%（比值比，1.28；95% 置信区间，1.12-1.45；P=0.0002），儿童肥胖风险增加 26%（比值比，1.26；95% 置信区间，1.16-1.37；P）
High salt intake is the major cause of raised blood pressure and accordingly leads to cardiovascular diseases. Recently, it has been shown that high salt intake is associated with an increased risk of obesity through sugar-sweetened beverage consumption. Increasing evidence also suggests a direct link. Our study aimed to determine whether there was a direct association between salt intake and obesity independent of energy intake. We analyzed the data from the rolling cross-sectional study-the UK National Diet and Nutrition Survey 2008/2009 to 2011/2012. We included 458 children (52% boys; age, 10 +/- 4 years) and 785 adults (47% men; age, 49 +/- 17 years) who had complete 24-hour urine collections. Energy intake was calculated from 4-day diary and misreporting was assessed by Goldberg method. The results showed that salt intake as measured by 24-hour urinary sodium was higher in overweight and obese individuals. A 1-g/d increase in salt intake was associated with an increase in the risk of obesity by 28% (odds ratio, 1.28; 95% confidence interval, 1.12-1.45; P=0.0002) in children and 26% (odds ratio, 1.26; 95% confidence interval, 1.16-1.37; P