Nucleocytoplasmic transport in yeast: a few roles for many actors
Nucleocytoplasmic transport in yeast: a few roles for many actors
复制标题
DOI：
10.1042/bst0380273
复制
发表时间：
2010-02-01
影响因子：
3.9
通讯作者：
Goldberg, Martin W.
中科院分区：
文献类型：
--
作者：
Fiserova, Jindriska;Goldberg, Martin W.
真核细胞已经发展出一系列高度受控的细胞核和细胞质之间的转运过程。本文综述了酵母细胞核质分子交换的最新研究进展。它集中在个别蛋白质，如核孔蛋白和核转运蛋白在易位过程中的作用，并将其与核孔复合物的组织如何有效地促进两个隔间之间的双向运输。
Eukaryotic cells have developed a series of highly controlled processes of transport between the nucleus and cytoplasm. The present review focuses on the latest advances in our understanding of nucleocytoplasmic exchange of molecules in yeast, a widely studied model organism in the field. It concentrates on the role of individual proteins such as nucleoporins and karyopherins in the translocation process and relates this to how the organization of the nuclear pore complex effectively facilitates the bidirectional transport between the two compartments.