A practical, robust approach to high-resolution breast ultrasound tomography
A practical, robust approach to high-resolution breast ultrasound tomography
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一种实用、稳健的高分辨率乳腺超声断层扫描方法
DOI：
10.1117/12.878690
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Huthwaite P
中科院分区：
文献类型：
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作者：
Huthwaite P
与乳房X光摄影的黄金标准相比，乳腺超声断层扫描有可能提高乳腺癌筛查和诊断的成本、安全性和可靠性。实现这一潜力的关键是开发成像算法，以揭示乳房及其机械特性的复杂解剖结构。最常用的解决方案是飞行时间层析成像，但由于存在衍射效应，分辨率较低。迭代全波反演法给出了一种获得更高分辨率的解决方案，但这些方法速度很慢，不能保证收敛到正确的解。HARBUT是一种用于健壮乳房超声层析成像的混合算法，它利用飞行时间成像和衍射层析成像的互补优势，产生了一种直接、快速、健壮和准确的高分辨率方法来重建通过乳房的声速。新的算法被证明可以用复杂的3D模拟的真实数据产生准确的重建，小到4毫米的质量是清晰可见的。
Breast ultrasound tomography has the potential to improve the cost, safety and reliability of breast cancer screening and diagnosis over the gold-standard of mammography. Vital to achieving this potential is the development of imaging algorithms to unravel the complex anatomy of the breast and its mechanical properties. The solution most commonly relied upon is Time-of-Flight Tomography but this exhibits low resolution due to the presence of diffraction effects. Iterative full-wave inversion methods present one solution to achieve higher resolution, but these are slow and are not guaranteed to converge to the correct solution. Presented here is HARBUT, the Hybrid Algorithm for Robust Breast Ultrasound Tomography, which utilises the complementary strengths of Time-of-Flight and Diffraction Tomography resulting in a direct, fast, robust and accurate high resolution method of reconstructing the sound-speed through the breast. The new algorithm is shown to produce accurate reconstructions with realistic data from a complex 3D simulation, with masses as small as 4mm being clearly visible.