Effect of Mastication Muscle Activity on Prefrontal Cortex NIRS Measurement: A Pilot Study.
Effect of Mastication Muscle Activity on Prefrontal Cortex NIRS Measurement: A Pilot Study.
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DOI：
10.1007/978-3-030-34461-0_17
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发表时间：
2020
影响因子：
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通讯作者：
K. Nakajima;T. Takeda;Maho Saito;M. Konno;Y. Kawano;Yoshihiro Suzuki;M. Nishino;Yoshiaki Matsuda;K. Ishigami;K. Sakatani
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文献类型：
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作者：
K. Nakajima;T. Takeda;Maho Saito;M. Konno;Y. Kawano;Yoshihiro Suzuki;M. Nishino;Yoshiaki Matsuda;K. Ishigami;K. Sakatani
NIRS信号的变化与局部脑血流量或氧合血红蛋白浓度的变化有关。另一方面，最近的研究揭示了咀嚼口香糖对认知能力，压力控制等的影响，这些影响伴随着前额叶皮层（PFC）的大脑活动。然而，这些关系仍然存在争议。为了评价咀嚼对PFC的影响，NIRS似乎是一种合适的成像方法。近红外光谱测定PFC时，表层组织（头皮、皮肤、肌肉）的血容量可能有一定的影响。本研究的目的是阐明咀嚼口香糖时颞前肌对近红外光谱信号的影响。8名健康志愿者参加了活动。使用了双通道NIRS（HOT-1000，NeU，日本），其可以区分深层组织和浅层组织中的总Hb浓度。除了3.0 cm的传统光电管间距外，Hot 1000还具有1.0 cm的短距离（近通道），可测量仅源自表面组织的NIRS信号。在正常探头设置中，NIRS探头放置在Fp1和Fp2处。将头戴式耳机向左移位，以便将左探头放置在左颞前肌上。在正常设置中，表面信号曲线没有显示出显著变化;然而，神经（在HOT-1000中计算和定义）和深层曲线显示在咀嚼口香糖任务期间增加。在偏离设置下，所有三个信号在任务期间都显示出显著的变化。在偏离探头设置中的总Hb浓度显著大于正常探头设置中的总Hb浓度（p <0.05）。当使用咀嚼口香糖作为任务时，最好仔细考虑探头位置，以便可以区分肌肉活动对NIRS信号的影响。
Changes in NIRS signals are related to changes in local cerebral blood flow or oxy-Hb concentration. On the other hand, recent studies have revealed the effect of chewing gum on cognitive performance, stress control etc. which accompanied brain activity in the prefrontal cortex (PFC). However, these relationships are still controversial. To evaluate the chewing effect on PFC, NIRS seems to be a suitable method of imaging such results. When measuring NIRS on PFC, blood volume in superficial tissues (scalp, skin, muscle) might have some affect. The aim of the present study was to clarify the effect of the anterior temporal muscle on NIRS signals during gum chewing. Eight healthy volunteers participated. Two-channel NIRS (HOT-1000, NeU, Japan), which can distinguish total-Hb concentrations in deep tissue and superficial tissue layers, was used. In addition to a conventional optode separation distance of 3.0 cm, Hot 1000 has a short distance of 1.0 cm (NEAR channel) to measure NIRS signals that originate exclusively from surface tissues. NIRS probes were placed at Fp1 and Fp2 in the normal probe setting. The headset was displaced to the left in order to allow the left probe to be placed over the left anterior temporal muscle. In the normal setting, the superficial signal curve shows no notable change; however, the neural (calculated and defined in HOT-1000) and deep curves show an increase during the gum chewing task. At the deviated setting, all three signals show marked changes during the task. Total-Hb concentration in the deviated probe setting is significantly large (p < 0.05) than that of in the normal probe setting. When using gum chewing as a task, it would be better to consider a probe position carefully so that the influence of muscle activity on NIRS signal can be distinguished.