New imaging tools to measure nephron number in vivo: opportunities for developmental nephrology.
New imaging tools to measure nephron number in vivo: opportunities for developmental nephrology.
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DOI：
10.1017/s204017442000001x
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发表时间：
2021-04
影响因子：
1.7
通讯作者：
Charlton JR
中科院分区：
文献类型：
--
作者：
Bennett KM;Baldelomar EJ;Morozov D;Chevalier RL;Charlton JR
The mammalian kidney is a complex organ, requiring the concerted function of up to millions of nephrons. The number of nephrons is constant after nephrogenesis during development, and nephron loss over a lifespan can lead to susceptibility to acute or chronic kidney disease. New technologies are under development to count individual nephrons in the kidney in vivo. This review outlines these technologies and highlights their relevance to studies of human renal development and disease.
