Visual Areas Exert Feedforward and Feedback Influences through Distinct Frequency Channels
Visual Areas Exert Feedforward and Feedback Influences through Distinct Frequency Channels
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DOI：
10.1016/j.neuron.2014.12.018
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发表时间：
2015-01-21
期刊：
影响因子：
16.2
通讯作者：
Fries, Pascal
中科院分区：
文献类型：
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作者：
Bastos, Andre Moraes;Vezoli, Julien;Fries, Pascal
视觉皮质区通过在前馈和反馈两个方向上的相互作用来支持认知功能。前馈影响传递感官信号，反馈影响根据当前行为环境调节前馈信号。我们研究了这些区域间的影响是否受到节奏同步的不同影响。我们将28对视觉区域的频率特异性定向影响与各自区域间投影的前馈或反馈特征的解剖度量相关联。这表明，在灵长类视觉系统中，前馈影响是通过theta波段（类似于4 Hz）和gamma波段（类似于60-80 Hz）同步进行的，反馈影响是通过β波段（类似于14-18 Hz）同步进行的。功能导向影响限制了类似于解剖层次的功能层次，但表现出任务依赖的动态变化，特别是在额叶区域的层次位置方面。我们的研究结果表明，前馈和反馈信号使用不同的频率通道，表明它们满足不同的通信需求。
Visual cortical areas subserve cognitive functions by interacting in both feedforward and feedback directions. While feedforward influences convey sensory signals, feedback influences modulate feedforward signaling according to the current behavioral context. We investigated whether these interareal influences are subserved differentially by rhythmic synchronization. We correlated frequency-specific directed influences among 28 pairs of visual areas with anatomical metrics of the feedforward or feedback character of the respective interareal projections. This revealed that in the primate visual system, feedforward influences are carried by theta-band (similar to 4 Hz) and gamma-band (similar to 60-80 Hz) synchronization, and feedback influences by beta-band (similar to 14-18 Hz) synchronization. The functional directed influences constrain a functional hierarchy similar to the anatomical hierarchy, but exhibiting task-dependent dynamic changes in particular with regard to the hierarchical positions of frontal areas. Our results demonstrate that feedforward and feedback signaling use distinct frequency channels, suggesting that they subserve differential communication requirements.